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Myeloid-Derived Suppressor Cells and Pulmonary Hypertension.
Bryant AJ, Mehrad B, Brusko TM, West JD, Moldawer LL. Bryant AJ, et al. Among authors: moldawer ll. Int J Mol Sci. 2018 Aug 3;19(8):2277. doi: 10.3390/ijms19082277. Int J Mol Sci. 2018. PMID: 30081463 Free PMC article. Review.
A checkpoint on innate myeloid cells in pulmonary arterial hypertension.
Bryant AJ, Fu C, Lu Y, Brantly ML, Mehrad B, Moldawer LL, Brusko TM, Brittain EL, West JD, Austin ED, Hamid R. Bryant AJ, et al. Among authors: moldawer ll. Pulm Circ. 2019 Jan-Mar;9(1):2045894018823528. doi: 10.1177/2045894018823528. Epub 2018 Dec 18. Pulm Circ. 2019. PMID: 30562157 Free PMC article. No abstract available.
Single-Cell RNA-seq of Human Myeloid-Derived Suppressor Cells in Late Sepsis Reveals Multiple Subsets With Unique Transcriptional Responses: A Pilot Study.
Darden DB, Bacher R, Brusko MA, Knight P, Hawkins RB, Cox MC, Dirain ML, Ungaro R, Nacionales DC, Rincon JC, Gauthier ML, Kladde M, Bihorac A, Brusko TM, Moore FA, Brakenridge SC, Mohr AM, Moldawer LL, Efron PA. Darden DB, et al. Among authors: moldawer ll. Shock. 2021 May 1;55(5):587-595. doi: 10.1097/SHK.0000000000001671. Shock. 2021. PMID: 33021571 Free PMC article.
A Novel Single Cell RNA-seq Analysis of Non-Myeloid Circulating Cells in Late Sepsis.
Darden DB, Dong X, Brusko MA, Kelly L, Fenner B, Rincon JC, Dirain ML, Ungaro R, Nacionales DC, Gauthier M, Kladde M, Brusko TM, Bihorac A, Moore FA, Loftus T, Bacher R, Moldawer LL, Mohr AM, Efron PA. Darden DB, et al. Among authors: moldawer ll. Front Immunol. 2021 Aug 16;12:696536. doi: 10.3389/fimmu.2021.696536. eCollection 2021. Front Immunol. 2021. PMID: 34484194 Free PMC article.
Human Pancreatic Cancer Cells Induce a MyD88-Dependent Stromal Response to Promote a Tumor-Tolerant Immune Microenvironment.
Delitto D, Delitto AE, DiVita BB, Pham K, Han S, Hartlage ER, Newby BN, Gerber MH, Behrns KE, Moldawer LL, Thomas RM, George TJ Jr, Brusko TM, Mathews CE, Liu C, Trevino JG, Hughes SJ, Wallet SM. Delitto D, et al. Among authors: moldawer ll. Cancer Res. 2017 Feb 1;77(3):672-683. doi: 10.1158/0008-5472.CAN-16-1765. Epub 2016 Nov 18. Cancer Res. 2017. PMID: 27864347 Free PMC article.
A hypolipoprotein sepsis phenotype indicates reduced lipoprotein antioxidant capacity, increased endothelial dysfunction and organ failure, and worse clinical outcomes.
Guirgis FW, Black LP, Henson M, Labilloy G, Smotherman C, Hopson C, Tfirn I, DeVos EL, Leeuwenburgh C, Moldawer L, Datta S, Brusko TM, Hester A, Bertrand A, Grijalva V, Arango-Esterhay A, Moore FA, Reddy ST. Guirgis FW, et al. Crit Care. 2021 Sep 17;25(1):341. doi: 10.1186/s13054-021-03757-5. Crit Care. 2021. PMID: 34535154 Free PMC article.
Myeloid-derived suppressor cell function and epigenetic expression evolves over time after surgical sepsis.
Hollen MK, Stortz JA, Darden D, Dirain ML, Nacionales DC, Hawkins RB, Cox MC, Lopez MC, Rincon JC, Ungaro R, Wang Z, Wu Q, Brumback B, Gauthier ML, Kladde M, Leeuwenburgh C, Segal M, Bihorac A, Brakenridge S, Moore FA, Baker HV, Mohr AM, Moldawer LL, Efron PA. Hollen MK, et al. Among authors: moldawer ll. Crit Care. 2019 Nov 13;23(1):355. doi: 10.1186/s13054-019-2628-x. Crit Care. 2019. PMID: 31722736 Free PMC article.
Human Myeloid-derived Suppressor Cells are Associated With Chronic Immune Suppression After Severe Sepsis/Septic Shock.
Mathias B, Delmas AL, Ozrazgat-Baslanti T, Vanzant EL, Szpila BE, Mohr AM, Moore FA, Brakenridge SC, Brumback BA, Moldawer LL, Efron PA; the Sepsis, Critical Illness Research Center Investigators. Mathias B, et al. Among authors: moldawer ll. Ann Surg. 2017 Apr;265(4):827-834. doi: 10.1097/SLA.0000000000001783. Ann Surg. 2017. PMID: 27163951 Free PMC article.
539 results