Martinez A - Search Results

1

Tau-Centric Multitarget Approach for Alzheimer's Disease: Development of First-in-Class Dual Glycogen Synthase Kinase 3β and Tau-Aggregation Inhibitors.

Gandini A, Bartolini M, Tedesco D, Martinez-Gonzalez L, Roca C, Campillo NE, Zaldivar-Diez J, Perez C, Zuccheri G, Miti A, Feoli A, Castellano S, Petralla S, Monti B, Rossi M, Moda F, Legname G, Martinez A, Bolognesi ML. Gandini A, et al. Among authors: martinez gonzalez l, martinez a. J Med Chem. 2018 Sep 13;61(17):7640-7656. doi: 10.1021/acs.jmedchem.8b00610. Epub 2018 Aug 24. J Med Chem. 2018. PMID: 30078314

2

First non-ATP competitive glycogen synthase kinase 3 beta (GSK-3beta) inhibitors: thiadiazolidinones (TDZD) as potential drugs for the treatment of Alzheimer's disease.

Martinez A, Alonso M, Castro A, Pérez C, Moreno FJ. Martinez A, et al. J Med Chem. 2002 Mar 14;45(6):1292-9. doi: 10.1021/jm011020u. J Med Chem. 2002. PMID: 11881998

3

Glycogen synthase kinase 3 (GSK-3) inhibitors as new promising drugs for diabetes, neurodegeneration, cancer, and inflammation.

Martinez A, Castro A, Dorronsoro I, Alonso M. Martinez A, et al. Med Res Rev. 2002 Jul;22(4):373-84. doi: 10.1002/med.10011. Med Res Rev. 2002. PMID: 12111750 Review.

4

Non-cholinergic pharmacotherapy approaches to the future treatment of Alzheimer's disease.

Castro A, Conde S, Rodriguez-Franco MI, Martinez A. Castro A, et al. Among authors: martinez a. Mini Rev Med Chem. 2002 Feb;2(1):37-50. doi: 10.2174/1389557023406610. Mini Rev Med Chem. 2002. PMID: 12369956 Review.

5

Benzothiadiazine dioxides (BTD) derivatives as non-nucleoside human cytomegalovirus (HCMV) inhibitors. study of structural requirements for biological activity.

Martinez A, Gil C, Castro A, Pérez C, Prieto C, Otero J. Martinez A, et al. Bioorg Med Chem. 2003 May 29;11(11):2395-402. doi: 10.1016/s0968-0896(03)00148-2. Bioorg Med Chem. 2003. PMID: 12735985

6

Benzothiadiazine dioxide human cytomegalovirus inhibitors: synthesis and antiviral evaluation of main heterocycle modified derivatives.

Martinez A, Gil C, Castro A, Bruno AM, Pérez C, Prieto C, Otero J. Martinez A, et al. Antivir Chem Chemother. 2003 Mar;14(2):107-14. doi: 10.1177/095632020301400206. Antivir Chem Chemother. 2003. PMID: 12856922 Free article.

7

Thienyl and phenyl alpha-halomethyl ketones: new inhibitors of glycogen synthase kinase (GSK-3beta) from a library of compound searching.

Conde S, Pérez DI, Martínez A, Perez C, Moreno FJ. Conde S, et al. Among authors: martinez a. J Med Chem. 2003 Oct 23;46(22):4631-3. doi: 10.1021/jm034108b. J Med Chem. 2003. PMID: 14561081

8

Design and synthesis of N-benzylpiperidine-purine derivatives as new dual inhibitors of acetyl- and butyrylcholinesterase.

Rodríguez-Franco MI, Fernández-Bachiller MI, Pérez C, Castro A, Martínez A. Rodríguez-Franco MI, et al. Among authors: martinez a. Bioorg Med Chem. 2005 Dec 15;13(24):6795-802. doi: 10.1016/j.bmc.2005.07.019. Epub 2005 Sep 23. Bioorg Med Chem. 2005. PMID: 16183292

9

SAR and 3D-QSAR studies on thiadiazolidinone derivatives: exploration of structural requirements for glycogen synthase kinase 3 inhibitors.

Martinez A, Alonso M, Castro A, Dorronsoro I, Gelpí JL, Luque FJ, Pérez C, Moreno FJ. Martinez A, et al. J Med Chem. 2005 Nov 17;48(23):7103-12. doi: 10.1021/jm040895g. J Med Chem. 2005. PMID: 16279768

10

Design, synthesis, and biological evaluation of dual binding site acetylcholinesterase inhibitors: new disease-modifying agents for Alzheimer's disease.

Muñoz-Ruiz P, Rubio L, García-Palomero E, Dorronsoro I, del Monte-Millán M, Valenzuela R, Usán P, de Austria C, Bartolini M, Andrisano V, Bidon-Chanal A, Orozco M, Luque FJ, Medina M, Martínez A. Muñoz-Ruiz P, et al. Among authors: martinez a. J Med Chem. 2005 Nov 17;48(23):7223-33. doi: 10.1021/jm0503289. J Med Chem. 2005. PMID: 16279781

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