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A new quinoline-based chemical probe inhibits the autophagy-related cysteine protease ATG4B.
Bosc D, Vezenkov L, Bortnik S, An J, Xu J, Choutka C, Hannigan AM, Kovacic S, Loo S, Clark PGK, Chen G, Guay-Ross RN, Yang K, Dragowska WH, Zhang F, Go NE, Leung A, Honson NS, Pfeifer TA, Gleave M, Bally M, Jones SJ, Gorski SM, Young RN. Bosc D, et al. Among authors: honson ns. Sci Rep. 2018 Aug 3;8(1):11653. doi: 10.1038/s41598-018-29900-x. Sci Rep. 2018. PMID: 30076329 Free PMC article.
Potent inhibition of tau fibrillization with a multivalent ligand.
Honson NS, Jensen JR, Darby MV, Kuret J. Honson NS, et al. Biochem Biophys Res Commun. 2007 Nov 9;363(1):229-34. doi: 10.1016/j.bbrc.2007.08.166. Epub 2007 Sep 6. Biochem Biophys Res Commun. 2007. PMID: 17854770 Free PMC article.
18 results