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HNF1A is a novel oncogene that regulates human pancreatic cancer stem cell properties.
Abel EV, Goto M, Magnuson B, Abraham S, Ramanathan N, Hotaling E, Alaniz AA, Kumar-Sinha C, Dziubinski ML, Urs S, Wang L, Shi J, Waghray M, Ljungman M, Crawford HC, Simeone DM. Abel EV, et al. Among authors: crawford hc. Elife. 2018 Aug 3;7:e33947. doi: 10.7554/eLife.33947. Elife. 2018. PMID: 30074477 Free PMC article.
Ductal pancreatic cancer modeling and drug screening using human pluripotent stem cell- and patient-derived tumor organoids.
Huang L, Holtzinger A, Jagan I, BeGora M, Lohse I, Ngai N, Nostro C, Wang R, Muthuswamy LB, Crawford HC, Arrowsmith C, Kalloger SE, Renouf DJ, Connor AA, Cleary S, Schaeffer DF, Roehrl M, Tsao MS, Gallinger S, Keller G, Muthuswamy SK. Huang L, et al. Among authors: crawford hc. Nat Med. 2015 Nov;21(11):1364-71. doi: 10.1038/nm.3973. Epub 2015 Oct 26. Nat Med. 2015. PMID: 26501191 Free PMC article.
PDX1 dynamically regulates pancreatic ductal adenocarcinoma initiation and maintenance.
Roy N, Takeuchi KK, Ruggeri JM, Bailey P, Chang D, Li J, Leonhardt L, Puri S, Hoffman MT, Gao S, Halbrook CJ, Song Y, Ljungman M, Malik S, Wright CV, Dawson DW, Biankin AV, Hebrok M, Crawford HC. Roy N, et al. Among authors: crawford hc. Genes Dev. 2016 Dec 15;30(24):2669-2683. doi: 10.1101/gad.291021.116. Genes Dev. 2016. PMID: 28087712 Free PMC article.
Epithelial-Stromal Interactions in Pancreatic Cancer.
Zhang Y, Crawford HC, Pasca di Magliano M. Zhang Y, et al. Among authors: crawford hc. Annu Rev Physiol. 2019 Feb 10;81:211-233. doi: 10.1146/annurev-physiol-020518-114515. Epub 2018 Nov 12. Annu Rev Physiol. 2019. PMID: 30418798 Review.
Macrophage-Released Pyrimidines Inhibit Gemcitabine Therapy in Pancreatic Cancer.
Halbrook CJ, Pontious C, Kovalenko I, Lapienyte L, Dreyer S, Lee HJ, Thurston G, Zhang Y, Lazarus J, Sajjakulnukit P, Hong HS, Kremer DM, Nelson BS, Kemp S, Zhang L, Chang D, Biankin A, Shi J, Frankel TL, Crawford HC, Morton JP, Pasca di Magliano M, Lyssiotis CA. Halbrook CJ, et al. Among authors: crawford hc. Cell Metab. 2019 Jun 4;29(6):1390-1399.e6. doi: 10.1016/j.cmet.2019.02.001. Epub 2019 Feb 28. Cell Metab. 2019. PMID: 30827862 Free PMC article.
ATDC is required for the initiation of KRAS-induced pancreatic tumorigenesis.
Wang L, Yang H, Zamperone A, Diolaiti D, Palmbos PL, Abel EV, Purohit V, Dolgalev I, Rhim AD, Ljungman M, Hadju CH, Halbrook CJ, Bar-Sagi D, di Magliano MP, Crawford HC, Simeone DM. Wang L, et al. Among authors: crawford hc. Genes Dev. 2019 Jun 1;33(11-12):641-655. doi: 10.1101/gad.323303.118. Epub 2019 May 2. Genes Dev. 2019. PMID: 31048544 Free PMC article.
Interleukin 22 Signaling Regulates Acinar Cell Plasticity to Promote Pancreatic Tumor Development in Mice.
Perusina Lanfranca M, Zhang Y, Girgis A, Kasselman S, Lazarus J, Kryczek I, Delrosario L, Rhim A, Koneva L, Sartor M, Sun L, Halbrook C, Nathan H, Shi J, Crawford HC, Pasca di Magliano M, Zou W, Frankel TL. Perusina Lanfranca M, et al. Among authors: crawford hc. Gastroenterology. 2020 Apr;158(5):1417-1432.e11. doi: 10.1053/j.gastro.2019.12.010. Epub 2019 Dec 14. Gastroenterology. 2020. PMID: 31843590 Free PMC article.
Carcinogenesis of Pancreatic Ductal Adenocarcinoma.
Storz P, Crawford HC. Storz P, et al. Among authors: crawford hc. Gastroenterology. 2020 Jun;158(8):2072-2081. doi: 10.1053/j.gastro.2020.02.059. Epub 2020 Mar 19. Gastroenterology. 2020. PMID: 32199881 Free PMC article. Review.
148 results