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Page 1
A functional Kv1.2-hERG chimaeric channel expressed in Pichia pastoris.
Dhillon MS, Cockcroft CJ, Munsey T, Smith KJ, Powell AJ, Carter P, Wrighton DC, Rong HL, Yusaf SP, Sivaprasadarao A. Dhillon MS, et al. Among authors: yusaf sp. Sci Rep. 2014 Feb 26;4:4201. doi: 10.1038/srep04201. Sci Rep. 2014. PMID: 24569544 Free PMC article.
Integration of lead optimization with crystallography for a membrane-bound ion channel target: discovery of a new class of AMPA receptor positive allosteric modulators.
Ward SE, Harries M, Aldegheri L, Austin NE, Ballantine S, Ballini E, Bradley DM, Bax BD, Clarke BP, Harris AJ, Harrison SA, Melarange RA, Mookherjee C, Mosley J, Dal Negro G, Oliosi B, Smith KJ, Thewlis KM, Woollard PM, Yusaf SP. Ward SE, et al. Among authors: yusaf sp. J Med Chem. 2011 Jan 13;54(1):78-94. doi: 10.1021/jm100679e. Epub 2010 Dec 3. J Med Chem. 2011. PMID: 21128618
Discovery of N-[(2S)-5-(6-fluoro-3-pyridinyl)-2,3-dihydro-1H-inden-2-yl]-2-propanesulfonamide, a novel clinical AMPA receptor positive modulator.
Ward SE, Harries M, Aldegheri L, Andreotti D, Ballantine S, Bax BD, Harris AJ, Harker AJ, Lund J, Melarange R, Mingardi A, Mookherjee C, Mosley J, Neve M, Oliosi B, Profeta R, Smith KJ, Smith PW, Spada S, Thewlis KM, Yusaf SP. Ward SE, et al. Among authors: yusaf sp. J Med Chem. 2010 Aug 12;53(15):5801-12. doi: 10.1021/jm1005429. J Med Chem. 2010. PMID: 20614889 Clinical Trial.
Structural determinants of drugs acting on the Nav1.8 channel.
Browne LE, Blaney FE, Yusaf SP, Clare JJ, Wray D. Browne LE, et al. Among authors: yusaf sp. J Biol Chem. 2009 Apr 17;284(16):10523-36. doi: 10.1074/jbc.M807569200. Epub 2009 Feb 19. J Biol Chem. 2009. PMID: 19233853 Free PMC article.
Characterisation of 5-HT3C, 5-HT3D and 5-HT3E receptor subunits: evolution, distribution and function.
Holbrook JD, Gill CH, Zebda N, Spencer JP, Leyland R, Rance KH, Trinh H, Balmer G, Kelly FM, Yusaf SP, Courtenay N, Luck J, Rhodes A, Modha S, Moore SE, Sanger GJ, Gunthorpe MJ. Holbrook JD, et al. Among authors: yusaf sp. J Neurochem. 2009 Jan;108(2):384-96. doi: 10.1111/j.1471-4159.2008.05775.x. Epub 2008 Nov 29. J Neurochem. 2009. PMID: 19012743 Free article.
Characterization of the human HCN1 channel and its inhibition by capsazepine.
Gill CH, Randall A, Bates SA, Hill K, Owen D, Larkman PM, Cairns W, Yusaf SP, Murdock PR, Strijbos PJ, Powell AJ, Benham CD, Davies CH. Gill CH, et al. Among authors: yusaf sp. Br J Pharmacol. 2004 Oct;143(3):411-21. doi: 10.1038/sj.bjp.0705945. Epub 2004 Sep 6. Br J Pharmacol. 2004. PMID: 15351778 Free PMC article.
15 results