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Cortactin deficiency causes increased RhoA/ROCK1-dependent actomyosin contractility, intestinal epithelial barrier dysfunction, and disproportionately severe DSS-induced colitis.
Citalán-Madrid AF, Vargas-Robles H, García-Ponce A, Shibayama M, Betanzos A, Nava P, Salinas-Lara C, Rottner K, Mennigen R, Schnoor M. Citalán-Madrid AF, et al. Among authors: mennigen r. Mucosal Immunol. 2017 Sep;10(5):1237-1247. doi: 10.1038/mi.2016.136. Epub 2017 Jan 25. Mucosal Immunol. 2017. PMID: 28120846 Free article.
PECAM-1 (CD 31) mediates transendothelial leukocyte migration in experimental colitis.
Rijcken E, Mennigen RB, Schaefer SD, Laukoetter MG, Anthoni C, Spiegel HU, Bruewer M, Senninger N, Krieglstein CF. Rijcken E, et al. Am J Physiol Gastrointest Liver Physiol. 2007 Aug;293(2):G446-52. doi: 10.1152/ajpgi.00097.2007. Epub 2007 May 17. Am J Physiol Gastrointest Liver Physiol. 2007. PMID: 17510197 Free article.
Immunoblockade of PSGL-1 attenuates established experimental murine colitis by reduction of leukocyte rolling.
Rijcken EM, Laukoetter MG, Anthoni C, Meier S, Mennigen R, Spiegel HU, Bruewer M, Senninger N, Vestweber D, Krieglstein CF. Rijcken EM, et al. Among authors: mennigen r. Am J Physiol Gastrointest Liver Physiol. 2004 Jul;287(1):G115-24. doi: 10.1152/ajpgi.00207.2003. Epub 2004 Mar 4. Am J Physiol Gastrointest Liver Physiol. 2004. PMID: 15001428 Free article.
Intestinal cancer risk in Crohn's disease: a meta-analysis.
Laukoetter MG, Mennigen R, Hannig CM, Osada N, Rijcken E, Vowinkel T, Krieglstein CF, Senninger N, Anthoni C, Bruewer M. Laukoetter MG, et al. Among authors: mennigen r. J Gastrointest Surg. 2011 Apr;15(4):576-83. doi: 10.1007/s11605-010-1402-9. Epub 2010 Dec 9. J Gastrointest Surg. 2011. PMID: 21152994
66 results