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Developmental and genetic regulation of the human cortex transcriptome illuminate schizophrenia pathogenesis.
Jaffe AE, Straub RE, Shin JH, Tao R, Gao Y, Collado-Torres L, Kam-Thong T, Xi HS, Quan J, Chen Q, Colantuoni C, Ulrich WS, Maher BJ, Deep-Soboslay A; BrainSeq Consortium; Cross AJ, Brandon NJ, Leek JT, Hyde TM, Kleinman JE, Weinberger DR. Jaffe AE, et al. Among authors: ulrich ws. Nat Neurosci. 2018 Aug;21(8):1117-1125. doi: 10.1038/s41593-018-0197-y. Epub 2018 Jul 26. Nat Neurosci. 2018. PMID: 30050107 Free PMC article.
Regional Heterogeneity in Gene Expression, Regulation, and Coherence in the Frontal Cortex and Hippocampus across Development and Schizophrenia.
Collado-Torres L, Burke EE, Peterson A, Shin J, Straub RE, Rajpurohit A, Semick SA, Ulrich WS; BrainSeq Consortium; Price AJ, Valencia C, Tao R, Deep-Soboslay A, Hyde TM, Kleinman JE, Weinberger DR, Jaffe AE. Collado-Torres L, et al. Among authors: ulrich ws. Neuron. 2019 Jul 17;103(2):203-216.e8. doi: 10.1016/j.neuron.2019.05.013. Epub 2019 Jun 4. Neuron. 2019. PMID: 31174959 Free PMC article.
Dissecting transcriptomic signatures of neuronal differentiation and maturation using iPSCs.
Burke EE, Chenoweth JG, Shin JH, Collado-Torres L, Kim SK, Micali N, Wang Y, Colantuoni C, Straub RE, Hoeppner DJ, Chen HY, Sellers A, Shibbani K, Hamersky GR, Diaz Bustamante M, Phan BN, Ulrich WS, Valencia C, Jaishankar A, Price AJ, Rajpurohit A, Semick SA, Bürli RW, Barrow JC, Hiler DJ, Page SC, Martinowich K, Hyde TM, Kleinman JE, Berman KF, Apud JA, Cross AJ, Brandon NJ, Weinberger DR, Maher BJ, McKay RDG, Jaffe AE. Burke EE, et al. Among authors: ulrich ws. Nat Commun. 2020 Jan 23;11(1):462. doi: 10.1038/s41467-019-14266-z. Nat Commun. 2020. PMID: 31974374 Free PMC article.
Association of Missense Mutation in FOLH1 With Decreased NAAG Levels and Impaired Working Memory Circuitry and Cognition.
Zink CF, Barker PB, Sawa A, Weinberger DR, Wang M, Quillian H, Ulrich WS, Chen Q, Jaffe AE, Kleinman JE, Hyde TM, Prettyman GE, Giegerich M, Carta K, van Ginkel M, Bigos KL. Zink CF, et al. Among authors: ulrich ws. Am J Psychiatry. 2020 Dec 1;177(12):1129-1139. doi: 10.1176/appi.ajp.2020.19111152. Am J Psychiatry. 2020. PMID: 33256444
Genome-wide meta-analyses reveal novel loci for verbal short-term memory and learning.
Lahti J, Tuominen S, Yang Q, Pergola G, Ahmad S, Amin N, Armstrong NJ, Beiser A, Bey K, Bis JC, Boerwinkle E, Bressler J, Campbell A, Campbell H, Chen Q, Corley J, Cox SR, Davies G, De Jager PL, Derks EM, Faul JD, Fitzpatrick AL, Fohner AE, Ford I, Fornage M, Gerring Z, Grabe HJ, Grodstein F, Gudnason V, Simonsick E, Holliday EG, Joshi PK, Kajantie E, Kaprio J, Karell P, Kleineidam L, Knol MJ, Kochan NA, Kwok JB, Leber M, Lam M, Lee T, Li S, Loukola A, Luck T, Marioni RE, Mather KA, Medland S, Mirza SS, Nalls MA, Nho K, O'Donnell A, Oldmeadow C, Painter J, Pattie A, Reppermund S, Risacher SL, Rose RJ, Sadashivaiah V, Scholz M, Satizabal CL, Schofield PW, Schraut KE, Scott RJ, Simino J, Smith AV, Smith JA, Stott DJ, Surakka I, Teumer A, Thalamuthu A, Trompet S, Turner ST, van der Lee SJ, Villringer A, Völker U, Wilson RS, Wittfeld K, Vuoksimaa E, Xia R, Yaffe K, Yu L, Zare H, Zhao W, Ames D, Attia J, Bennett DA, Brodaty H, Chasman DI, Goldman AL, Hayward C, Ikram MA, Jukema JW, Kardia SLR, Lencz T, Loeffler M, Mattay VS, Palotie A, Psaty BM, Ramirez A, Ridker PM, Riedel-Heller SG, Sachdev PS, Saykin AJ, Scherer M, Schofield PR, Sidney S, Starr JM, Trollor J, Ulrich W, Wagner M, Wei… See abstract for full author list ➔ Lahti J, et al. Mol Psychiatry. 2022 Nov;27(11):4419-4431. doi: 10.1038/s41380-022-01710-8. Epub 2022 Aug 16. Mol Psychiatry. 2022. PMID: 35974141 Free PMC article.
Analysis of the caudate nucleus transcriptome in individuals with schizophrenia highlights effects of antipsychotics and new risk genes.
Benjamin KJM, Chen Q, Jaffe AE, Stolz JM, Collado-Torres L, Huuki-Myers LA, Burke EE, Arora R, Feltrin AS, Barbosa AR, Radulescu E, Pergola G, Shin JH, Ulrich WS, Deep-Soboslay A, Tao R; BrainSeq Consortium; Hyde TM, Kleinman JE, Erwin JA, Weinberger DR, Paquola ACM. Benjamin KJM, et al. Among authors: ulrich ws. Nat Neurosci. 2022 Nov;25(11):1559-1568. doi: 10.1038/s41593-022-01182-7. Epub 2022 Nov 1. Nat Neurosci. 2022. PMID: 36319771 Free PMC article.
Changes in patterns of age-related network connectivity are associated with risk for schizophrenia.
Passiatore R, Antonucci LA, DeRamus TP, Fazio L, Stolfa G, Sportelli L, Kikidis GC, Blasi G, Chen Q, Dukart J, Goldman AL, Mattay VS, Popolizio T, Rampino A, Sambataro F, Selvaggi P, Ulrich W; Apulian Network on Risk for Psychosis; Weinberger DR, Bertolino A, Calhoun VD, Pergola G. Passiatore R, et al. Proc Natl Acad Sci U S A. 2023 Aug 8;120(32):e2221533120. doi: 10.1073/pnas.2221533120. Epub 2023 Aug 1. Proc Natl Acad Sci U S A. 2023. PMID: 37527347 Free PMC article.
Dopamine and schizophrenia from bench to bedside: Discovery of a striatal co-expression risk gene set that predicts in vivo measures of striatal function.
Sportelli L, Eisenberg DP, Passiatore R, D'Ambrosio E, Antonucci LA, Chen Q, Czarapata J, Goldman AL, Gregory M, Griffiths K, Hyde TM, Kleinman JE, Pardiñas AF, Parihar M, Popolizio T, Rampino A, Shin JH, Veronese M, Ulrich WS, Zink CF, Bertolino A, Howes OD, Berman KF, Weinberger DR, Pergola G. Sportelli L, et al. Among authors: ulrich ws. bioRxiv [Preprint]. 2023 Sep 21:2023.09.20.558594. doi: 10.1101/2023.09.20.558594. bioRxiv. 2023. PMID: 37786720 Free PMC article. Preprint.
13 results