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Accumulation of 8,9-unsaturated sterols drives oligodendrocyte formation and remyelination.
Hubler Z, Allimuthu D, Bederman I, Elitt MS, Madhavan M, Allan KC, Shick HE, Garrison E, T Karl M, Factor DC, Nevin ZS, Sax JL, Thompson MA, Fedorov Y, Jin J, Wilson WK, Giera M, Bracher F, Miller RH, Tesar PJ, Adams DJ. Hubler Z, et al. Among authors: adams dj. Nature. 2018 Aug;560(7718):372-376. doi: 10.1038/s41586-018-0360-3. Epub 2018 Jul 25. Nature. 2018. PMID: 30046109 Free PMC article.
Chemical Screening Identifies Enhancers of Mutant Oligodendrocyte Survival and Unmasks a Distinct Pathological Phase in Pelizaeus-Merzbacher Disease.
Elitt MS, Shick HE, Madhavan M, Allan KC, Clayton BLL, Weng C, Miller TE, Factor DC, Barbar L, Nawash BS, Nevin ZS, Lager AM, Li Y, Jin F, Adams DJ, Tesar PJ. Elitt MS, et al. Among authors: adams dj. Stem Cell Reports. 2018 Sep 11;11(3):711-726. doi: 10.1016/j.stemcr.2018.07.015. Epub 2018 Aug 23. Stem Cell Reports. 2018. PMID: 30146490 Free PMC article.
A miRNA-Mediated Approach to Dissect the Complexity of Tumor-Initiating Cell Function and Identify miRNA-Targeting Drugs.
Belur Nagaraj A, Joseph P, Ponting E, Fedorov Y, Singh S, Cole A, Lee W, Yoon E, Baccarini A, Scacheri P, Buckanovich R, Adams DJ, Drapkin R, Brown BD, DiFeo A. Belur Nagaraj A, et al. Among authors: adams dj. Stem Cell Reports. 2019 Jan 8;12(1):122-134. doi: 10.1016/j.stemcr.2018.12.002. Stem Cell Reports. 2019. PMID: 30629937 Free PMC article.
Ex vivo screen identifies CDK12 as a metastatic vulnerability in osteosarcoma.
Bayles I, Krajewska M, Pontius WD, Saiakhova A, Morrow JJ, Bartels C, Lu J, Faber ZJ, Fedorov Y, Hong ES, Karnuta JM, Rubin B, Adams DJ, George RE, Scacheri PC. Bayles I, et al. Among authors: adams dj. J Clin Invest. 2019 Oct 1;129(10):4377-4392. doi: 10.1172/JCI127718. J Clin Invest. 2019. PMID: 31498151 Free PMC article.
Cell Type-Specific Intralocus Interactions Reveal Oligodendrocyte Mechanisms in MS.
Factor DC, Barbeau AM, Allan KC, Hu LR, Madhavan M, Hoang AT, Hazel KEA, Hall PA, Nisraiyya S, Najm FJ, Miller TE, Nevin ZS, Karl RT, Lima BR, Song Y, Sibert AG, Dhillon GK, Volsko C, Bartels CF, Adams DJ, Dutta R, Gallagher MD, Phu W, Kozlenkov A, Dracheva S, Scacheri PC, Tesar PJ, Corradin O. Factor DC, et al. Among authors: adams dj. Cell. 2020 Apr 16;181(2):382-395.e21. doi: 10.1016/j.cell.2020.03.002. Epub 2020 Apr 3. Cell. 2020. PMID: 32246942 Free PMC article.
1,144 results