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Design of Selective sPLA2-X Inhibitor (-)-2-{2-[Carbamoyl-6-(trifluoromethoxy)-1H-indol-1-yl]pyridine-2-yl}propanoic Acid.
Giordanetto F, Knerr L, Nordberg P, Pettersen D, Selmi N, Beisel HG, de la Motte H, Månsson Å, Dahlström M, Broddefalk J, Saarinen G, Klingegård F, Hurt-Camejo E, Rosengren B, Wikström J, Wågberg M, Brengdahl J, Rohman M, Sandmark J, Åkerud T, Roth RG, Jansen F, Ahlqvist M. Giordanetto F, et al. Among authors: rohman m. ACS Med Chem Lett. 2018 Jun 23;9(7):600-605. doi: 10.1021/acsmedchemlett.7b00507. eCollection 2018 Jul 12. ACS Med Chem Lett. 2018. PMID: 30034586 Free PMC article.
Discovery of a Series of Indole-2 Carboxamides as Selective Secreted Phospholipase A2 Type X (sPLA2-X) Inhibitors.
Knerr L, Giordanetto F, Nordberg P, Pettersen D, Selmi N, Beisel HG, de la Motte H, Olsson T, Perkins TDJ, Herslöf M, Månsson Å, Dahlström M, Starke I, Broddefalk J, Saarinen G, Klingegård F, Hurt-Camejo E, Rosengren B, Brengdahl J, Jansen F, Rohman M, Sandmark J, Hallberg K, Åkerud T, Roth RG, Ahlqvist M. Knerr L, et al. Among authors: rohman m. ACS Med Chem Lett. 2018 Jun 23;9(7):594-599. doi: 10.1021/acsmedchemlett.7b00505. eCollection 2018 Jul 12. ACS Med Chem Lett. 2018. PMID: 30034585 Free PMC article.
Validation of low-volume 1536-well assay-ready compound plates.
Eriksson H, Brengdahl J, Sandström P, Rohman M, Becker B. Eriksson H, et al. Among authors: rohman m. J Biomol Screen. 2009 Jun;14(5):468-75. doi: 10.1177/1087057109335324. Epub 2009 May 21. J Biomol Screen. 2009. PMID: 19470713
Discovery of the Oral Leukotriene C4 Synthase Inhibitor (1S,2S)-2-({5-[(5-Chloro-2,4-difluorophenyl)(2-fluoro-2-methylpropyl)amino]-3-methoxypyrazin-2-yl}carbonyl)cyclopropanecarboxylic Acid (AZD9898) as a New Treatment for Asthma.
Munck Af Rosenschöld M, Johannesson P, Nikitidis A, Tyrchan C, Chang HF, Rönn R, Chapman D, Ullah V, Nikitidis G, Glader P, Käck H, Bonn B, Wågberg F, Björkstrand E, Andersson U, Swedin L, Rohman M, Andreasson T, Bergström EL, Jiang F, Zhou XH, Lundqvist AJ, Malmberg A, Ek M, Gordon E, Pettersen A, Ripa L, Davis AM. Munck Af Rosenschöld M, et al. Among authors: rohman m. J Med Chem. 2019 Sep 12;62(17):7769-7787. doi: 10.1021/acs.jmedchem.9b00555. Epub 2019 Aug 30. J Med Chem. 2019. PMID: 31415176
High-quality cost-effective compound management support for HTS.
Zaragoza-Sundqvist M, Eriksson H, Rohman M, Greasley PJ. Zaragoza-Sundqvist M, et al. Among authors: rohman m. J Biomol Screen. 2009 Jun;14(5):509-14. doi: 10.1177/1087057109336589. Epub 2009 Jun 1. J Biomol Screen. 2009. PMID: 19487769
158 results