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Discovery of a Series of Indole-2 Carboxamides as Selective Secreted Phospholipase A2 Type X (sPLA2-X) Inhibitors.
Knerr L, Giordanetto F, Nordberg P, Pettersen D, Selmi N, Beisel HG, de la Motte H, Olsson T, Perkins TDJ, Herslöf M, Månsson Å, Dahlström M, Starke I, Broddefalk J, Saarinen G, Klingegård F, Hurt-Camejo E, Rosengren B, Brengdahl J, Jansen F, Rohman M, Sandmark J, Hallberg K, Åkerud T, Roth RG, Ahlqvist M. Knerr L, et al. Among authors: ahlqvist m. ACS Med Chem Lett. 2018 Jun 23;9(7):594-599. doi: 10.1021/acsmedchemlett.7b00505. eCollection 2018 Jul 12. ACS Med Chem Lett. 2018. PMID: 30034585 Free PMC article.
Design of Selective sPLA2-X Inhibitor (-)-2-{2-[Carbamoyl-6-(trifluoromethoxy)-1H-indol-1-yl]pyridine-2-yl}propanoic Acid.
Giordanetto F, Knerr L, Nordberg P, Pettersen D, Selmi N, Beisel HG, de la Motte H, Månsson Å, Dahlström M, Broddefalk J, Saarinen G, Klingegård F, Hurt-Camejo E, Rosengren B, Wikström J, Wågberg M, Brengdahl J, Rohman M, Sandmark J, Åkerud T, Roth RG, Jansen F, Ahlqvist M. Giordanetto F, et al. Among authors: ahlqvist m. ACS Med Chem Lett. 2018 Jun 23;9(7):600-605. doi: 10.1021/acsmedchemlett.7b00507. eCollection 2018 Jul 12. ACS Med Chem Lett. 2018. PMID: 30034586 Free PMC article.
Critical differences in drug metabolic properties of human hepatic cellular models, including primary human hepatocytes, stem cell derived hepatocytes, and hepatoma cell lines.
Kvist AJ, Kanebratt KP, Walentinsson A, Palmgren H, O'Hara M, Björkbom A, Andersson LC, Ahlqvist M, Andersson TB. Kvist AJ, et al. Among authors: ahlqvist m. Biochem Pharmacol. 2018 Sep;155:124-140. doi: 10.1016/j.bcp.2018.06.026. Epub 2018 Jun 25. Biochem Pharmacol. 2018. PMID: 29953844
Software-aided structural elucidation in drug discovery.
Ahlqvist M, Leandersson C, Hayes MA, Zamora I, Thompson RA. Ahlqvist M, et al. Rapid Commun Mass Spectrom. 2015 Nov 15;29(21):2083-9. doi: 10.1002/rcm.7364. Rapid Commun Mass Spectrom. 2015. PMID: 26443410
Effects of Tenapanor on Cytochrome P450-Mediated Drug-Drug Interactions.
Johansson S, Rosenbaum DP, Ahlqvist M, Rollison H, Knutsson M, Stefansson B, Elebring M. Johansson S, et al. Among authors: ahlqvist m. Clin Pharmacol Drug Dev. 2017 Sep;6(5):466-475. doi: 10.1002/cpdd.346. Epub 2017 Mar 16. Clin Pharmacol Drug Dev. 2017. PMID: 28301096 Free PMC article. Clinical Trial.
Meeting report of the 4th European biotransformation workshop.
Walles M, Pähler A, Isin EM, Ahlqvist MM. Walles M, et al. Among authors: ahlqvist mm. Xenobiotica. 2024 Jan 4:1-6. doi: 10.1080/00498254.2024.2302547. Online ahead of print. Xenobiotica. 2024. PMID: 38178690 Review.
The predictive value of highly malignant EEG patterns after cardiac arrest: evaluation of the ERC-ESICM recommendations.
Turella S, Dankiewicz J, Friberg H, Jakobsen JC, Leithner C, Levin H, Lilja G, Moseby-Knappe M, Nielsen N, Rossetti AO, Sandroni C, Zubler F, Cronberg T, Westhall E; TTM2-trial investigators. Turella S, et al. Intensive Care Med. 2024 Jan;50(1):90-102. doi: 10.1007/s00134-023-07280-9. Epub 2024 Jan 3. Intensive Care Med. 2024. PMID: 38172300 Free PMC article.
34 results