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Disruption of an enhancer associated with addictive behaviour within the cannabinoid receptor-1 gene suggests a possible role in alcohol intake, cannabinoid response and anxiety-related behaviour.
Hay EA, McEwan A, Wilson D, Barrett P, D'Agostino G, Pertwee RG, MacKenzie A. Hay EA, et al. Among authors: mackenzie a. Psychoneuroendocrinology. 2019 Nov;109:104407. doi: 10.1016/j.psyneuen.2019.104407. Epub 2019 Aug 13. Psychoneuroendocrinology. 2019. PMID: 31445429 Free PMC article.
Early and reversible changes to the hippocampal proteome in mice on a high-fat diet.
McLean FH, Campbell FM, Sergi D, Grant C, Morris AC, Hay EA, MacKenzie A, Mayer CD, Langston RF, Williams LM. McLean FH, et al. Among authors: mackenzie a. Nutr Metab (Lond). 2019 Aug 23;16:57. doi: 10.1186/s12986-019-0387-y. eCollection 2019. Nutr Metab (Lond). 2019. PMID: 31462902 Free PMC article.
CRISPR disruption and UK Biobank analysis of a highly conserved polymorphic enhancer suggests a role in male anxiety and ethanol intake.
McEwan AR, Davidson C, Hay E, Turnbull Y, Erickson JC, Marini P, Wilson D, McIntosh AM, Adams MJ, Murgatroyd C, Barrett P, Delibegovic M, Clarke TK, MacKenzie A. McEwan AR, et al. Among authors: mackenzie a. Mol Psychiatry. 2021 Jun;26(6):2263-2276. doi: 10.1038/s41380-020-0707-7. Epub 2020 Mar 13. Mol Psychiatry. 2021. PMID: 32203157
1,285 results