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Small molecule disruption of G protein βγ subunit signaling reprograms human macrophage phenotype and prevents autoimmune myocarditis in rats.
Karuppagounder V, Bajpai A, Meng S, Arumugam S, Sreedhar R, Giridharan VV, Guha A, Bhimaraj A, Youker KA, Palaniyandi SS, Karmouty-Quintana H, Kamal F, Spiller KL, Watanabe K, Thandavarayan RA. Karuppagounder V, et al. Among authors: palaniyandi ss. PLoS One. 2018 Jul 19;13(7):e0200697. doi: 10.1371/journal.pone.0200697. eCollection 2018. PLoS One. 2018. PMID: 30024944 Free PMC article.
Modulation of Macrophage Polarization and HMGB1-TLR2/TLR4 Cascade Plays a Crucial Role for Cardiac Remodeling in Senescence-Accelerated Prone Mice.
Karuppagounder V, Giridharan VV, Arumugam S, Sreedhar R, Palaniyandi SS, Krishnamurthy P, Quevedo J, Watanabe K, Konishi T, Thandavarayan RA. Karuppagounder V, et al. Among authors: palaniyandi ss. PLoS One. 2016 Apr 12;11(4):e0152922. doi: 10.1371/journal.pone.0152922. eCollection 2016. PLoS One. 2016. PMID: 27070323 Free PMC article.
Candesartan cilexetil protects from cardiac myosin induced cardiotoxicity via reduction of endoplasmic reticulum stress and apoptosis in rats: involvement of ACE2-Ang (1-7)-mas axis.
Arumugam S, Thandavarayan RA, Palaniyandi SS, Giridharan VV, Arozal W, Sari FR, Soetikno V, Harima M, Suzuki K, Kodama M, Watanabe K. Arumugam S, et al. Among authors: palaniyandi ss. Toxicology. 2012 Jan 27;291(1-3):139-45. doi: 10.1016/j.tox.2011.11.008. Epub 2011 Nov 23. Toxicology. 2012. PMID: 22120037
Quercetin offers cardioprotection against progression of experimental autoimmune myocarditis by suppression of oxidative and endoplasmic reticulum stress via endothelin-1/MAPK signalling.
Arumugam S, Thandavarayan RA, Arozal W, Sari FR, Giridharan VV, Soetikno V, Palaniyandi SS, Harima M, Suzuki K, Nagata M, Tagaki R, Kodama M, Watanabe K. Arumugam S, et al. Among authors: palaniyandi ss. Free Radic Res. 2012 Feb;46(2):154-63. doi: 10.3109/10715762.2011.647010. Epub 2012 Jan 23. Free Radic Res. 2012. PMID: 22145946
Depletion of 14-3-3 protein exacerbates cardiac oxidative stress, inflammation and remodeling process via modulation of MAPK/NF-ĸB signaling pathways after streptozotocin-induced diabetes mellitus.
Thandavarayan RA, Giridharan VV, Sari FR, Arumugam S, Veeraveedu PT, Pandian GN, Palaniyandi SS, Ma M, Suzuki K, Gurusamy N, Watanabe K. Thandavarayan RA, et al. Among authors: palaniyandi ss. Cell Physiol Biochem. 2011;28(5):911-22. doi: 10.1159/000335805. Epub 2011 Dec 15. Cell Physiol Biochem. 2011. PMID: 22178943 Free article.
Beneficial effects of edaravone, a novel antioxidant, in rats with dilated cardiomyopathy.
Arumugam S, Thandavarayan RA, Veeraveedu PT, Nakamura T, Arozal W, Sari FR, Giridharan VV, Soetikno V, Palaniyandi SS, Harima M, Suzuki K, Nagata M, Kodama M, Watanabe K. Arumugam S, et al. Among authors: palaniyandi ss. J Cell Mol Med. 2012 Sep;16(9):2176-85. doi: 10.1111/j.1582-4934.2012.01526.x. J Cell Mol Med. 2012. PMID: 22268705 Free PMC article.
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