Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

Search Results

134 results

Filters applied: . Clear all
Results are displayed in a computed author sort order. The Results By Year timeline is not available.
Page 1
Nonselective Chemical Inhibition of Sec7 Domain-Containing ARF GTPase Exchange Factors.
Mishev K, Lu Q, Denoo B, Peurois F, Dejonghe W, Hullaert J, De Rycke R, Boeren S, Bretou M, De Munck S, Sharma I, Goodman K, Kalinowska K, Storme V, Nguyen LSL, Drozdzecki A, Martins S, Nerinckx W, Audenaert D, Vert G, Madder A, Otegui MS, Isono E, Savvides SN, Annaert W, De Vries S, Cherfils J, Winne J, Russinova E. Mishev K, et al. Among authors: savvides sn. Plant Cell. 2018 Oct;30(10):2573-2593. doi: 10.1105/tpc.18.00145. Epub 2018 Jul 17. Plant Cell. 2018. PMID: 30018157 Free PMC article.
Rare Antagonistic Leptin Variants and Severe, Early-Onset Obesity.
Funcke JB, Moepps B, Roos J, von Schnurbein J, Verstraete K, Fröhlich-Reiterer E, Kohlsdorf K, Nunziata A, Brandt S, Tsirigotaki A, Dansercoer A, Suppan E, Haris B, Debatin KM, Savvides SN, Farooqi IS, Hussain K, Gierschik P, Fischer-Posovszky P, Wabitsch M. Funcke JB, et al. Among authors: savvides sn. N Engl J Med. 2023 Jun 15;388(24):2253-2261. doi: 10.1056/NEJMoa2204041. N Engl J Med. 2023. PMID: 37314706
Sensory-Neuropathy-Causing Mutations in ATL3 Cause Aberrant ER Membrane Tethering.
Krols M, Detry S, Asselbergh B, Almeida-Souza L, Kremer A, Lippens S, De Rycke R, De Winter V, Müller FJ, Kurth I, McMahon HT, Savvides SN, Timmerman V, Janssens S. Krols M, et al. Among authors: savvides sn. Cell Rep. 2018 May 15;23(7):2026-2038. doi: 10.1016/j.celrep.2018.04.071. Cell Rep. 2018. PMID: 29768202 Free article.
Disruption of endocytosis through chemical inhibition of clathrin heavy chain function.
Dejonghe W, Sharma I, Denoo B, De Munck S, Lu Q, Mishev K, Bulut H, Mylle E, De Rycke R, Vasileva M, Savatin DV, Nerinckx W, Staes A, Drozdzecki A, Audenaert D, Yperman K, Madder A, Friml J, Van Damme D, Gevaert K, Haucke V, Savvides SN, Winne J, Russinova E. Dejonghe W, et al. Among authors: savvides sn. Nat Chem Biol. 2019 Jun;15(6):641-649. doi: 10.1038/s41589-019-0262-1. Epub 2019 Apr 22. Nat Chem Biol. 2019. PMID: 31011214 Free PMC article.
Endeavors towards transformation of M. tuberculosis thymidylate kinase (MtbTMPK) inhibitors into potential antimycobacterial agents.
Jian Y, Merceron R, De Munck S, Forbes HE, Hulpia F, Risseeuw MDP, Van Hecke K, Savvides SN, Munier-Lehmann H, Boshoff HIM, Van Calenbergh S. Jian Y, et al. Among authors: savvides sn. Eur J Med Chem. 2020 Nov 15;206:112659. doi: 10.1016/j.ejmech.2020.112659. Epub 2020 Jul 24. Eur J Med Chem. 2020. PMID: 32823003 Free PMC article.
Distinct EH domains of the endocytic TPLATE complex confer lipid and protein binding.
Yperman K, Papageorgiou AC, Merceron R, De Munck S, Bloch Y, Eeckhout D, Jiang Q, Tack P, Grigoryan R, Evangelidis T, Van Leene J, Vincze L, Vandenabeele P, Vanhaecke F, Potocký M, De Jaeger G, Savvides SN, Tripsianes K, Pleskot R, Van Damme D. Yperman K, et al. Among authors: savvides sn. Nat Commun. 2021 May 24;12(1):3050. doi: 10.1038/s41467-021-23314-6. Nat Commun. 2021. PMID: 34031427 Free PMC article.
Structural basis of cytokine-mediated activation of ALK family receptors.
De Munck S, Provost M, Kurikawa M, Omori I, Mukohyama J, Felix J, Bloch Y, Abdel-Wahab O, Bazan JF, Yoshimi A, Savvides SN. De Munck S, et al. Among authors: savvides sn. Nature. 2021 Dec;600(7887):143-147. doi: 10.1038/s41586-021-03959-5. Epub 2021 Oct 13. Nature. 2021. PMID: 34646012 Free PMC article.
Improving de novo protein binder design with deep learning.
Bennett NR, Coventry B, Goreshnik I, Huang B, Allen A, Vafeados D, Peng YP, Dauparas J, Baek M, Stewart L, DiMaio F, De Munck S, Savvides SN, Baker D. Bennett NR, et al. Among authors: savvides sn. Nat Commun. 2023 May 6;14(1):2625. doi: 10.1038/s41467-023-38328-5. Nat Commun. 2023. PMID: 37149653 Free PMC article.
134 results