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Nonselective Chemical Inhibition of Sec7 Domain-Containing ARF GTPase Exchange Factors.
Mishev K, Lu Q, Denoo B, Peurois F, Dejonghe W, Hullaert J, De Rycke R, Boeren S, Bretou M, De Munck S, Sharma I, Goodman K, Kalinowska K, Storme V, Nguyen LSL, Drozdzecki A, Martins S, Nerinckx W, Audenaert D, Vert G, Madder A, Otegui MS, Isono E, Savvides SN, Annaert W, De Vries S, Cherfils J, Winne J, Russinova E. Mishev K, et al. Among authors: nerinckx w. Plant Cell. 2018 Oct;30(10):2573-2593. doi: 10.1105/tpc.18.00145. Epub 2018 Jul 17. Plant Cell. 2018. PMID: 30018157 Free PMC article.
Disruption of endocytosis through chemical inhibition of clathrin heavy chain function.
Dejonghe W, Sharma I, Denoo B, De Munck S, Lu Q, Mishev K, Bulut H, Mylle E, De Rycke R, Vasileva M, Savatin DV, Nerinckx W, Staes A, Drozdzecki A, Audenaert D, Yperman K, Madder A, Friml J, Van Damme D, Gevaert K, Haucke V, Savvides SN, Winne J, Russinova E. Dejonghe W, et al. Among authors: nerinckx w. Nat Chem Biol. 2019 Jun;15(6):641-649. doi: 10.1038/s41589-019-0262-1. Epub 2019 Apr 22. Nat Chem Biol. 2019. PMID: 31011214 Free PMC article.
Necrostatin-1 analogues: critical issues on the specificity, activity and in vivo use in experimental disease models.
Takahashi N, Duprez L, Grootjans S, Cauwels A, Nerinckx W, DuHadaway JB, Goossens V, Roelandt R, Van Hauwermeiren F, Libert C, Declercq W, Callewaert N, Prendergast GC, Degterev A, Yuan J, Vandenabeele P. Takahashi N, et al. Among authors: nerinckx w. Cell Death Dis. 2012 Nov 29;3(11):e437. doi: 10.1038/cddis.2012.176. Cell Death Dis. 2012. PMID: 23190609 Free PMC article.
Tozasertib Analogues as Inhibitors of Necroptotic Cell Death.
Hofmans S, Devisscher L, Martens S, Van Rompaey D, Goossens K, Divert T, Nerinckx W, Takahashi N, De Winter H, Van Der Veken P, Goossens V, Vandenabeele P, Augustyns K. Hofmans S, et al. Among authors: nerinckx w. J Med Chem. 2018 Mar 8;61(5):1895-1920. doi: 10.1021/acs.jmedchem.7b01449. Epub 2018 Feb 20. J Med Chem. 2018. PMID: 29437386
34 results