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Serine Synthesis via PHGDH Is Essential for Heme Production in Endothelial Cells.
Cell Metab. 2018 Oct 2;28(4):573-587.e13. doi: 10.1016/j.cmet.2018.06.009. Epub 2018 Jul 12.
Cell Metab. 2018.
PMID: 30017355
Free article.
Aspartate is an endogenous metabolic limitation for tumour growth.
Sullivan LB, Luengo A, Danai LV, Bush LN, Diehl FF, Hosios AM, Lau AN, Elmiligy S, Malstrom S, Lewis CA, Vander Heiden MG.
Sullivan LB, et al. Among authors: diehl ff.
Nat Cell Biol. 2018 Jul;20(7):782-788. doi: 10.1038/s41556-018-0125-0. Epub 2018 Jun 25.
Nat Cell Biol. 2018.
PMID: 29941931
Free PMC article.
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Cellular redox state constrains serine synthesis and nucleotide production to impact cell proliferation.
Diehl FF, Lewis CA, Fiske BP, Vander Heiden MG.
Diehl FF, et al.
Nat Metab. 2019 Sep;1(9):861-867. doi: 10.1038/s42255-019-0108-x. Epub 2019 Sep 16.
Nat Metab. 2019.
PMID: 31598584
Free PMC article.
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Mitochondrial NADPH is a pro at Pro synthesis.
Diehl FF, Vander Heiden MG.
Diehl FF, et al.
Nat Metab. 2021 Apr;3(4):453-455. doi: 10.1038/s42255-021-00381-z.
Nat Metab. 2021.
PMID: 33833464
No abstract available.
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Targeting serine hydroxymethyltransferases 1 and 2 for T-cell acute lymphoblastic leukemia therapy.
Pikman Y, Ocasio-Martinez N, Alexe G, Dimitrov B, Kitara S, Diehl FF, Robichaud AL, Conway AS, Ross L, Su A, Ling F, Qi J, Roti G, Lewis CA, Puissant A, Vander Heiden MG, Stegmaier K.
Pikman Y, et al. Among authors: diehl ff.
Leukemia. 2022 Feb;36(2):348-360. doi: 10.1038/s41375-021-01361-8. Epub 2021 Aug 2.
Leukemia. 2022.
PMID: 34341479
Free PMC article.
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Nucleotide imbalance decouples cell growth from cell proliferation.
Diehl FF, Miettinen TP, Elbashir R, Nabel CS, Darnell AM, Do BT, Manalis SR, Lewis CA, Vander Heiden MG.
Diehl FF, et al.
Nat Cell Biol. 2022 Aug;24(8):1252-1264. doi: 10.1038/s41556-022-00965-1. Epub 2022 Aug 4.
Nat Cell Biol. 2022.
PMID: 35927450
Free PMC article.
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The bidirectional relationship between metabolism and cell cycle control.
Diehl FF, Sapp KM, Vander Heiden MG.
Diehl FF, et al.
Trends Cell Biol. 2024 Feb;34(2):136-149. doi: 10.1016/j.tcb.2023.05.012. Epub 2023 Jun 27.
Trends Cell Biol. 2024.
PMID: 37385879
Review.
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Modulation of CrbS-Dependent Activation of the Acetate Switch in Vibrio cholerae.
Muzhingi I, Prado C, Sylla M, Diehl FF, Nguyen DK, Servos MM, Flores Ramos S, Purdy AE.
Muzhingi I, et al. Among authors: diehl ff.
J Bacteriol. 2018 Nov 6;200(23):e00380-18. doi: 10.1128/JB.00380-18. Print 2018 Dec 1.
J Bacteriol. 2018.
PMID: 30224439
Free PMC article.
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