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Page 1
Antisense oligonucleotides extend survival and reverse decrement in muscle response in ALS models.
McCampbell A, Cole T, Wegener AJ, Tomassy GS, Setnicka A, Farley BJ, Schoch KM, Hoye ML, Shabsovich M, Sun L, Luo Y, Zhang M, Comfort N, Wang B, Amacker J, Thankamony S, Salzman DW, Cudkowicz M, Graham DL, Bennett CF, Kordasiewicz HB, Swayze EE, Miller TM. McCampbell A, et al. Among authors: schoch km. J Clin Invest. 2018 Aug 1;128(8):3558-3567. doi: 10.1172/JCI99081. Epub 2018 Jul 16. J Clin Invest. 2018. PMID: 30010620 Free PMC article.
Tau reduction prevents neuronal loss and reverses pathological tau deposition and seeding in mice with tauopathy.
DeVos SL, Miller RL, Schoch KM, Holmes BB, Kebodeaux CS, Wegener AJ, Chen G, Shen T, Tran H, Nichols B, Zanardi TA, Kordasiewicz HB, Swayze EE, Bennett CF, Diamond MI, Miller TM. DeVos SL, et al. Among authors: schoch km. Sci Transl Med. 2017 Jan 25;9(374):eaag0481. doi: 10.1126/scitranslmed.aag0481. Sci Transl Med. 2017. PMID: 28123067 Free PMC article.
MicroRNA Profiling Reveals Marker of Motor Neuron Disease in ALS Models.
Hoye ML, Koval ED, Wegener AJ, Hyman TS, Yang C, O'Brien DR, Miller RL, Cole T, Schoch KM, Shen T, Kunikata T, Richard JP, Gutmann DH, Maragakis NJ, Kordasiewicz HB, Dougherty JD, Miller TM. Hoye ML, et al. Among authors: schoch km. J Neurosci. 2017 May 31;37(22):5574-5586. doi: 10.1523/JNEUROSCI.3582-16.2017. Epub 2017 Apr 17. J Neurosci. 2017. PMID: 28416596 Free PMC article.
Protein production is an early biomarker for RNA-targeted therapies.
Self WK, Schoch KM, Alex J, Barthélemy N, Bollinger JG, Sato C, Cole T, Kordasiewicz HB, Swayze E, Bateman RJ, Miller TM. Self WK, et al. Among authors: schoch km. Ann Clin Transl Neurol. 2018 Oct 14;5(12):1492-1504. doi: 10.1002/acn3.657. eCollection 2018 Dec. Ann Clin Transl Neurol. 2018. PMID: 30564616 Free PMC article.
Is presymptomatic ALS perivascular?
Kreple CJ, Schoch KM, Miller TM. Kreple CJ, et al. Among authors: schoch km. Nat Med. 2021 Apr;27(4):585-586. doi: 10.1038/s41591-021-01311-y. Nat Med. 2021. PMID: 33859434 No abstract available.
Astrocytic 4R tau expression drives astrocyte reactivity and dysfunction.
Ezerskiy LA, Schoch KM, Sato C, Beltcheva M, Horie K, Rigo F, Martynowicz R, Karch CM, Bateman RJ, Miller TM. Ezerskiy LA, et al. Among authors: schoch km. JCI Insight. 2022 Jan 11;7(1):e152012. doi: 10.1172/jci.insight.152012. JCI Insight. 2022. PMID: 34874917 Free PMC article.
22 results