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Improved radiosynthesis and preliminary in vivo evaluation of the 11C-labeled tetrazine [11C]AE-1 for pretargeted PET imaging.
Stéen EJL, Jørgensen JT, Petersen IN, Nørregaard K, Lehel S, Shalgunov V, Birke A, Edem PE, L'Estrade ET, Hansen HD, Villadsen J, Erlandsson M, Ohlsson T, Yazdani A, Valliant JF, Kristensen JL, Barz M, Knudsen GM, Kjær A, Herth MM. Stéen EJL, et al. Bioorg Med Chem Lett. 2019 Apr 15;29(8):986-990. doi: 10.1016/j.bmcl.2019.02.014. Epub 2019 Feb 13. Bioorg Med Chem Lett. 2019. PMID: 30795854 Free article.
Trans-Cyclooctene-Functionalized PeptoBrushes with Improved Reaction Kinetics of the Tetrazine Ligation for Pretargeted Nuclear Imaging.
Stéen EJL, Jørgensen JT, Johann K, Nørregaard K, Sohr B, Svatunek D, Birke A, Shalgunov V, Edem PE, Rossin R, Seidl C, Schmid F, Robillard MS, Kristensen JL, Mikula H, Barz M, Kjær A, Herth MM. Stéen EJL, et al. ACS Nano. 2020 Jan 28;14(1):568-584. doi: 10.1021/acsnano.9b06905. Epub 2020 Jan 2. ACS Nano. 2020. PMID: 31820928 Free PMC article.
Lipophilicity and Click Reactivity Determine the Performance of Bioorthogonal Tetrazine Tools in Pretargeted In Vivo Chemistry.
Stéen EJL, Jørgensen JT, Denk C, Battisti UM, Nørregaard K, Edem PE, Bratteby K, Shalgunov V, Wilkovitsch M, Svatunek D, Poulie CBM, Hvass L, Simón M, Wanek T, Rossin R, Robillard M, Kristensen JL, Mikula H, Kjaer A, Herth MM. Stéen EJL, et al. ACS Pharmacol Transl Sci. 2021 Feb 16;4(2):824-833. doi: 10.1021/acsptsci.1c00007. eCollection 2021 Apr 9. ACS Pharmacol Transl Sci. 2021. PMID: 33860205 Free PMC article.
Convenient Entry to 18F-Labeled Amines through the Staudinger Reduction.
Stéen EJL, Shalgunov V, Denk C, Mikula H, Kjær A, Kristensen JL, Herth MM. Stéen EJL, et al. European J Org Chem. 2019 Feb 28;2019(8):1722-1725. doi: 10.1002/ejoc.201801457. Epub 2019 Jan 22. European J Org Chem. 2019. PMID: 31007573 Free PMC article.
Development of a simple proton nuclear magnetic resonance-based procedure to estimate the approximate distribution coefficient at physiological pH (logD7.4): Evaluation and comparison to existing practices.
Stéen EJL, Nyberg N, Lehel S, Andersen VL, Di Pilato P, Knudsen GM, Kristensen JL, Herth MM. Stéen EJL, et al. Bioorg Med Chem Lett. 2017 Jan 15;27(2):319-322. doi: 10.1016/j.bmcl.2016.11.048. Epub 2016 Nov 18. Bioorg Med Chem Lett. 2017. PMID: 27908763
A scaffold replacement approach towards new sirtuin 2 inhibitors.
Seifert T, Malo M, Kokkola T, Stéen EJL, Meinander K, Wallén EAA, Jarho EM, Luthman K. Seifert T, et al. Among authors: steen ejl. Bioorg Med Chem. 2020 Jan 15;28(2):115231. doi: 10.1016/j.bmc.2019.115231. Epub 2019 Nov 30. Bioorg Med Chem. 2020. PMID: 31848116 Free article.
Novel Thienopyrimidine-Based PET Tracers for P2Y12 Receptor Imaging in the Brain.
van der Wildt B, Janssen B, Pekošak A, Stéen EJL, Schuit RC, Kooijman EJM, Beaino W, Vugts DJ, Windhorst AD. van der Wildt B, et al. Among authors: steen ejl. ACS Chem Neurosci. 2021 Dec 1;12(23):4465-4474. doi: 10.1021/acschemneuro.1c00641. Epub 2021 Nov 10. ACS Chem Neurosci. 2021. PMID: 34757711 Free PMC article.
11 results