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Nitro-fatty acid formation and metabolism.
Nitric Oxide. 2018 Sep 1;79:38-44. doi: 10.1016/j.niox.2018.07.003. Epub 2018 Jul 10.
Nitric Oxide. 2018.
PMID: 30006146
Free PMC article.
Review.
Nitro-fatty acids are formed in response to virus infection and are potent inhibitors of STING palmitoylation and signaling.
Hansen AL, Buchan GJ, Rühl M, Mukai K, Salvatore SR, Ogawa E, Andersen SD, Iversen MB, Thielke AL, Gunderstofte C, Motwani M, Møller CT, Jakobsen AS, Fitzgerald KA, Roos J, Lin R, Maier TJ, Goldbach-Mansky R, Miner CA, Qian W, Miner JJ, Rigby RE, Rehwinkel J, Jakobsen MR, Arai H, Taguchi T, Schopfer FJ, Olagnier D, Holm CK.
Hansen AL, et al. Among authors: buchan gj.
Proc Natl Acad Sci U S A. 2018 Aug 14;115(33):E7768-E7775. doi: 10.1073/pnas.1806239115. Epub 2018 Jul 30.
Proc Natl Acad Sci U S A. 2018.
PMID: 30061387
Free PMC article.
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Nitroalkene fatty acids modulate bile acid metabolism and lung function in obese asthma.
Manni ML, Heinrich VA, Buchan GJ, O'Brien JP, Uvalle C, Cechova V, Koudelka A, Ukani D, Rawas-Qalaji M, Oury TD, Hart R, Ellgass M, Mullett SJ, Fajt ML, Wenzel SE, Holguin F, Freeman BA, Wendell SG.
Manni ML, et al. Among authors: buchan gj.
Sci Rep. 2021 Sep 7;11(1):17788. doi: 10.1038/s41598-021-96471-9.
Sci Rep. 2021.
PMID: 34493738
Free PMC article.
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Primary saturation of α, β-unsaturated carbonyl containing fatty acids does not abolish electrophilicity.
Snyder NW, O'Brien J, Singh B, Buchan G, Arroyo AD, Liu X, Bostwick A, Varner EL, Angajala A, Sobol RW, Blair IA, Mesaros C, Wendell SG.
Snyder NW, et al.
Chem Biol Interact. 2021 Dec 1;350:109689. doi: 10.1016/j.cbi.2021.109689. Epub 2021 Oct 8.
Chem Biol Interact. 2021.
PMID: 34634267
Free PMC article.
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Lipoxin A4 yields an electrophilic 15-oxo metabolite that mediates FPR2 receptor-independent anti-inflammatory signaling.
Koudelka A, Buchan GJ, Cechova V, O'Brien JP, Liu H, Woodcock SR, Mullett SJ, Zhang C, Freeman BA, Gelhaus SL.
Koudelka A, et al. Among authors: buchan gj.
bioRxiv [Preprint]. 2024 Feb 7:2024.02.06.579101. doi: 10.1101/2024.02.06.579101.
bioRxiv. 2024.
PMID: 38370667
Free PMC article.
Preprint.
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The C-terminal domain of SRA1p has a fold more similar to PRP18 than to an RRM and does not directly bind to the SRA1 RNA STR7 region.
Bilinovich SM, Davis CM, Morris DL, Ray LA, Prokop JW, Buchan GJ, Leeper TC.
Bilinovich SM, et al. Among authors: buchan gj.
J Mol Biol. 2014 Apr 17;426(8):1753-65. doi: 10.1016/j.jmb.2014.01.007. Epub 2014 Jan 29.
J Mol Biol. 2014.
PMID: 24486611
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