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Quantitative integration of epigenomic variation and transcription factor binding using MAmotif toolkit identifies an important role of IRF2 as transcription activator at gene promoters.
Sun H, Wang J, Gong Z, Yao J, Wang Y, Xu J, Yuan GC, Zhang Y, Shao Z. Sun H, et al. Among authors: wang j, wang y. Cell Discov. 2018 Jul 10;4:38. doi: 10.1038/s41421-018-0045-y. eCollection 2018. Cell Discov. 2018. PMID: 30002873 Free PMC article. No abstract available.
Amyloid-β induces hepatic insulin resistance in vivo via JAK2.
Zhang Y, Zhou B, Deng B, Zhang F, Wu J, Wang Y, Le Y, Zhai Q. Zhang Y, et al. Among authors: wang y. Diabetes. 2013 Apr;62(4):1159-66. doi: 10.2337/db12-0670. Epub 2012 Dec 6. Diabetes. 2013. PMID: 23223021 Free PMC article.
Down-regulation of Risa improves insulin sensitivity by enhancing autophagy.
Wang Y, Hu Y, Sun C, Zhuo S, He Z, Wang H, Yan M, Liu J, Luan Y, Dai C, Yang Y, Huang R, Zhou B, Zhang F, Zhai Q. Wang Y, et al. Among authors: wang h. FASEB J. 2016 Sep;30(9):3133-45. doi: 10.1096/fj.201500058R. Epub 2016 Jun 1. FASEB J. 2016. PMID: 27251173
Taken together, the data demonstrate that Risa regulates insulin sensitivity by affecting autophagy and suggest that Risa is a potential target for treating insulin-resistance-related diseases.-Wang, Y., Hu, Y., Sun, C., Zhuo, S., He, Z., Wang, H., Yan …
Taken together, the data demonstrate that Risa regulates insulin sensitivity by affecting autophagy and suggest that Risa is a potential tar …
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