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Discovery of CA-4948, an Orally Bioavailable IRAK4 Inhibitor for Treatment of Hematologic Malignancies.
Gummadi VR, Boruah A, Ainan BR, Vare BR, Manda S, Gondle HP, Kumar SN, Mukherjee S, Gore ST, Krishnamurthy NR, Marappan S, Nayak SS, Nellore K, Balasubramanian WR, Bhumireddy A, Giri S, Gopinath S, Samiulla DS, Daginakatte G, Basavaraju A, Chelur S, Eswarappa R, Belliappa C, Subramanya HS, Booher RN, Ramachandra M, Samajdar S. Gummadi VR, et al. Among authors: samiulla ds. ACS Med Chem Lett. 2020 Oct 14;11(12):2374-2381. doi: 10.1021/acsmedchemlett.0c00255. eCollection 2020 Dec 10. ACS Med Chem Lett. 2020. PMID: 33335659 Free PMC article.
Rational selection of structurally diverse natural product scaffolds with favorable ADME properties for drug discovery.
Samiulla DS, Vaidyanathan VV, Arun PC, Balan G, Blaze M, Bondre S, Chandrasekhar G, Gadakh A, Kumar R, Kharvi G, Kim HO, Kumar S, Malikayil JA, Moger M, Mone MK, Nagarjuna P, Ogbu C, Pendhalkar D, Rao AV, Rao GV, Sarma VK, Shaik S, Sharma GV, Singh S, Sreedhar C, Sonawane R, Timmanna U, Hardy LW. Samiulla DS, et al. Mol Divers. 2005;9(1-3):131-9. doi: 10.1007/s11030-005-1297-7. Mol Divers. 2005. PMID: 15789560
Discovery of Pyridyl Bis(oxy)dibenzimidamide Derivatives as Selective Matriptase Inhibitors.
Goswami R, Mukherjee S, Wohlfahrt G, Ghadiyaram C, Nagaraj J, Chandra BR, Sistla RK, Satyam LK, Samiulla DS, Moilanen A, Subramanya HS, Ramachandra M. Goswami R, et al. Among authors: samiulla ds. ACS Med Chem Lett. 2013 Oct 7;4(12):1152-7. doi: 10.1021/ml400213v. eCollection 2013 Dec 12. ACS Med Chem Lett. 2013. PMID: 24900621 Free PMC article.
Structure-guided discovery of 2-aryl/pyridin-2-yl-1H-indole derivatives as potent and selective hepsin inhibitors.
Goswami R, Wohlfahrt G, Törmäkangas O, Moilanen A, Lakshminarasimhan A, Nagaraj J, Arumugam KN, Mukherjee S, Chacko AR, Krishnamurthy NR, Jaleel M, Palakurthy RK, Samiulla DS, Ramachandra M. Goswami R, et al. Among authors: samiulla ds. Bioorg Med Chem Lett. 2015 Nov 15;25(22):5309-14. doi: 10.1016/j.bmcl.2015.09.042. Epub 2015 Sep 21. Bioorg Med Chem Lett. 2015. PMID: 26421993
Trypsin inhibitory activity of Lawsonia inermis.
Yogisha S, Samiulla DS, Prashanth D, Padmaja R, Amit A. Yogisha S, et al. Among authors: samiulla ds. Fitoterapia. 2002 Dec;73(7-8):690-1. doi: 10.1016/s0367-326x(02)00214-9. Fitoterapia. 2002. PMID: 12490230
15 results