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Dual-Specificity Tyrosine Phosphorylation-Regulated Kinase 1A (DYRK1A) Inhibitors as Potential Therapeutics.
J Med Chem. 2018 Nov 21;61(22):9791-9810. doi: 10.1021/acs.jmedchem.8b00185. Epub 2018 Jul 20.
J Med Chem. 2018.
PMID: 29985601
Review.
Discovery of a Novel Template, 7-Substituted 7-Deaza-4'-Thioadenosine Derivatives as Multi-Kinase Inhibitors.
Mashelkar KK, Byun WS, Ko H, Sung K, Tripathi SK, An S, Yum YA, Kwon JY, Kim M, Kim G, Kwon EJ, Lee HW, Noh M, Lee SK, Jeong LS.
Mashelkar KK, et al.
Pharmaceuticals (Basel). 2021 Dec 10;14(12):1290. doi: 10.3390/ph14121290.
Pharmaceuticals (Basel). 2021.
PMID: 34959689
Free PMC article.
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In Silico Discovery of 5'-Modified 7-Deoxy-7-ethynyl-4'-thioadenosine as a HASPIN Inhibitor and Its Synergistic Anticancer Effect with the PLK1 Inhibitor.
Kwon EJ, Mashelkar KK, Seo J, Shin YZ, Sung K, Jang SC, Cheon SW, Lee H, Lee HW, Kim G, Han BW, Lee SK, Jeong LS, Cha HJ.
Kwon EJ, et al. Among authors: mashelkar kk.
ACS Cent Sci. 2023 May 11;9(6):1140-1149. doi: 10.1021/acscentsci.3c00332. eCollection 2023 Jun 28.
ACS Cent Sci. 2023.
PMID: 37396870
Free PMC article.
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