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Titin-based mechanosensing modulates muscle hypertrophy.
van der Pijl R, Strom J, Conijn S, Lindqvist J, Labeit S, Granzier H, Ottenheijm C. van der Pijl R, et al. J Cachexia Sarcopenia Muscle. 2018 Oct;9(5):947-961. doi: 10.1002/jcsm.12319. Epub 2018 Jul 5. J Cachexia Sarcopenia Muscle. 2018. PMID: 29978560 Free PMC article.
Positive End-Expiratory Pressure Ventilation Induces Longitudinal Atrophy in Diaphragm Fibers.
Lindqvist J, van den Berg M, van der Pijl R, Hooijman PE, Beishuizen A, Elshof J, de Waard M, Girbes A, Spoelstra-de Man A, Shi ZH, van den Brom C, Bogaards S, Shen S, Strom J, Granzier H, Kole J, Musters RJP, Paul MA, Heunks LMA, Ottenheijm CAC. Lindqvist J, et al. Among authors: van den berg m, van der pijl r, van den brom c. Am J Respir Crit Care Med. 2018 Aug 15;198(4):472-485. doi: 10.1164/rccm.201709-1917OC. Am J Respir Crit Care Med. 2018. PMID: 29578749 Free PMC article.
KBTBD13 is an actin-binding protein that modulates muscle kinetics.
de Winter JM, Molenaar JP, Yuen M, van der Pijl R, Shen S, Conijn S, van de Locht M, Willigenburg M, Bogaards SJ, van Kleef ES, Lassche S, Persson M, Rassier DE, Sztal TE, Ruparelia AA, Oorschot V, Ramm G, Hall TE, Xiong Z, Johnson CN, Li F, Kiss B, Lozano-Vidal N, Boon RA, Marabita M, Nogara L, Blaauw B, Rodenburg RJ, Küsters B, Doorduin J, Beggs AH, Granzier H, Campbell K, Ma W, Irving T, Malfatti E, Romero NB, Bryson-Richardson RJ, van Engelen BG, Voermans NC, Ottenheijm CA. de Winter JM, et al. Among authors: van de locht m, van der pijl r, van kleef es, van engelen bg. J Clin Invest. 2020 Feb 3;130(2):754-767. doi: 10.1172/JCI124000. J Clin Invest. 2020. PMID: 31671076 Free PMC article.
Preserved single muscle fiber specific force in facioscapulohumeral muscular dystrophy.
Lassche S, Voermans NC, van der Pijl R, van den Berg M, Heerschap A, van Hees H, Kusters B, van der Maarel SM, Ottenheijm CAC, van Engelen BGM. Lassche S, et al. Among authors: van den berg m, van der maarel sm, van hees h, van engelen bgm, van der pijl r. Neurology. 2020 Mar 17;94(11):e1157-e1170. doi: 10.1212/WNL.0000000000008977. Epub 2020 Jan 21. Neurology. 2020. PMID: 31964688 Free PMC article.
Nebulin nemaline myopathy recapitulated in a compound heterozygous mouse model with both a missense and a nonsense mutation in Neb.
Laitila JM, McNamara EL, Wingate CD, Goullee H, Ross JA, Taylor RL, van der Pijl R, Griffiths LM, Harries R, Ravenscroft G, Clayton JS, Sewry C, Lawlor MW, Ottenheijm CAC, Bakker AJ, Ochala J, Laing NG, Wallgren-Pettersson C, Pelin K, Nowak KJ. Laitila JM, et al. Among authors: van der pijl r. Acta Neuropathol Commun. 2020 Feb 17;8(1):18. doi: 10.1186/s40478-020-0893-1. Acta Neuropathol Commun. 2020. PMID: 32066503 Free PMC article.
Triggering typical nemaline myopathy with compound heterozygous nebulin mutations reveals myofilament structural changes as pathomechanism.
Lindqvist J, Ma W, Li F, Hernandez Y, Kolb J, Kiss B, Tonino P, van der Pijl R, Karimi E, Gong H, Strom J, Hourani Z, Smith JE 3rd, Ottenheijm C, Irving T, Granzier H. Lindqvist J, et al. Among authors: van der pijl r. Nat Commun. 2020 Jun 1;11(1):2699. doi: 10.1038/s41467-020-16526-9. Nat Commun. 2020. PMID: 32483185 Free PMC article.
Titin N2A: More than a signaling node?
van der Pijl RJ, Ottenheijm CAC. van der Pijl RJ, et al. J Gen Physiol. 2021 Jul 5;153(7):e202112904. doi: 10.1085/jgp.202112904. Epub 2021 Jun 3. J Gen Physiol. 2021. PMID: 34081095 Free PMC article.
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