Hughes RA - Search Results

1

Targeting TrkB with a Brain-Derived Neurotrophic Factor Mimetic Promotes Myelin Repair in the Brain.

Fletcher JL, Wood RJ, Nguyen J, Norman EML, Jun CMK, Prawdiuk AR, Biemond M, Nguyen HTH, Northfield SE, Hughes RA, Gonsalvez DG, Xiao J, Murray SS. Fletcher JL, et al. Among authors: hughes ra. J Neurosci. 2018 Aug 8;38(32):7088-7099. doi: 10.1523/JNEUROSCI.0487-18.2018. Epub 2018 Jul 5. J Neurosci. 2018. PMID: 29976621 Free PMC article.

2

A small peptide mimetic of brain-derived neurotrophic factor promotes peripheral myelination.

Xiao J, Hughes RA, Lim JY, Wong AW, Ivanusic JJ, Ferner AH, Kilpatrick TJ, Murray SS. Xiao J, et al. Among authors: hughes ra. J Neurochem. 2013 May;125(3):386-98. doi: 10.1111/jnc.12168. Epub 2013 Feb 24. J Neurochem. 2013. PMID: 23350698 Free article.

3

A Brain-Derived Neurotrophic Factor-Based p75^NTR Peptide Mimetic Ameliorates Experimental Autoimmune Neuritis Induced Axonal Pathology and Demyelination.

Gonsalvez DG, Tran G, Fletcher JL, Hughes RA, Hodgkinson S, Wood RJ, Yoo SW, De Silva M, Agnes WW, McLean C, Kennedy P, Kilpatrick TJ, Murray SS, Xiao J. Gonsalvez DG, et al. Among authors: hughes ra. eNeuro. 2017 Jul 4;4(3):ENEURO.0142-17.2017. doi: 10.1523/ENEURO.0142-17.2017. eCollection 2017 May-Jun. eNeuro. 2017. PMID: 28680965 Free PMC article.

4

Design of a conformationally defined and proteolytically stable circular mimetic of brain-derived neurotrophic factor.

Fletcher JM, Morton CJ, Zwar RA, Murray SS, O'Leary PD, Hughes RA. Fletcher JM, et al. Among authors: hughes ra. J Biol Chem. 2008 Nov 28;283(48):33375-83. doi: 10.1074/jbc.M802789200. Epub 2008 Sep 22. J Biol Chem. 2008. PMID: 18809686 Free PMC article.

5

TDP6, a brain-derived neurotrophic factor-based trkB peptide mimetic, promotes oligodendrocyte myelination.

Wong AW, Giuffrida L, Wood R, Peckham H, Gonsalvez D, Murray SS, Hughes RA, Xiao J. Wong AW, et al. Among authors: hughes ra. Mol Cell Neurosci. 2014 Nov;63:132-40. doi: 10.1016/j.mcn.2014.10.002. Mol Cell Neurosci. 2014. PMID: 25461619

6

1,3-Dichloroacetone: A Robust Reagent for Preparing Bicyclic Peptides.

Lin Q, Hopper D, Zhang H, Sfyris Qoon J, Shen Z, Karas JA, Hughes RA, Northfield SE. Lin Q, et al. Among authors: hughes ra. ACS Omega. 2020 Jan 17;5(4):1840-1850. doi: 10.1021/acsomega.9b03152. eCollection 2020 Feb 4. ACS Omega. 2020. PMID: 32039320 Free PMC article.

7

Esterase-Mediated Sustained Release of Peptide-Based Therapeutics from a Self-Assembled Injectable Hydrogel.

Kulkarni K, Minehan RL, Gamot T, Coleman HA, Bowles S, Lin Q, Hopper D, Northfield SE, Hughes RA, Widdop RE, Aguilar MI, Parkington HC, Del Borgo MP. Kulkarni K, et al. Among authors: hughes ra. ACS Appl Mater Interfaces. 2021 Dec 15;13(49):58279-58290. doi: 10.1021/acsami.1c14150. Epub 2021 Nov 10. ACS Appl Mater Interfaces. 2021. PMID: 34756031

8

Novel monocyclic and bicyclic loop mimetics of brain-derived neurotrophic factor.

Fletcher JM, Hughes RA. Fletcher JM, et al. Among authors: hughes ra. J Pept Sci. 2006 Aug;12(8):515-24. doi: 10.1002/psc.760. J Pept Sci. 2006. PMID: 16680799

9

Design of potent peptide mimetics of brain-derived neurotrophic factor.

O'Leary PD, Hughes RA. O'Leary PD, et al. Among authors: hughes ra. J Biol Chem. 2003 Jul 11;278(28):25738-44. doi: 10.1074/jbc.M303209200. Epub 2003 May 2. J Biol Chem. 2003. PMID: 12730196 Free article.

10

Structure-activity relationships of conformationally constrained peptide analogues of loop 2 of brain-derived neurotrophic factor.

O'Leary PD, Hughes RA. O'Leary PD, et al. Among authors: hughes ra. J Neurochem. 1998 Apr;70(4):1712-21. doi: 10.1046/j.1471-4159.1998.70041712.x. J Neurochem. 1998. PMID: 9523590 Free article.

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