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Page 1
Cited4 is a sex-biased mediator of the antidiabetic glitazone response in adipocyte progenitors.
Bayindir-Buchhalter I, Wolff G, Lerch S, Sijmonsma T, Schuster M, Gronych J, Billeter AT, Babaei R, Krunic D, Ketscher L, Spielmann N, Hrabe de Angelis M, Ruas JL, Müller-Stich BP, Heikenwalder M, Lichter P, Herzig S, Vegiopoulos A. Bayindir-Buchhalter I, et al. Among authors: heikenwalder m. EMBO Mol Med. 2018 Aug;10(8):e8613. doi: 10.15252/emmm.201708613. EMBO Mol Med. 2018. PMID: 29973382 Free PMC article.
USP18 lack in microglia causes destructive interferonopathy of the mouse brain.
Goldmann T, Zeller N, Raasch J, Kierdorf K, Frenzel K, Ketscher L, Basters A, Staszewski O, Brendecke SM, Spiess A, Tay TL, Kreutz C, Timmer J, Mancini GM, Blank T, Fritz G, Biber K, Lang R, Malo D, Merkler D, Heikenwälder M, Knobeloch KP, Prinz M. Goldmann T, et al. Among authors: heikenwalder m. EMBO J. 2015 Jun 12;34(12):1612-29. doi: 10.15252/embj.201490791. Epub 2015 Apr 20. EMBO J. 2015. PMID: 25896511 Free PMC article.
The necroptosis-inducing kinase RIPK3 dampens adipose tissue inflammation and glucose intolerance.
Gautheron J, Vucur M, Schneider AT, Severi I, Roderburg C, Roy S, Bartneck M, Schrammen P, Diaz MB, Ehling J, Gremse F, Heymann F, Koppe C, Lammers T, Kiessling F, Van Best N, Pabst O, Courtois G, Linkermann A, Krautwald S, Neumann UP, Tacke F, Trautwein C, Green DR, Longerich T, Frey N, Luedde M, Bluher M, Herzig S, Heikenwalder M, Luedde T. Gautheron J, et al. Among authors: heikenwalder m. Nat Commun. 2016 Jun 21;7:11869. doi: 10.1038/ncomms11869. Nat Commun. 2016. PMID: 27323669 Free PMC article.
A liver stress-endocrine nexus promotes metabolic integrity during dietary protein dilution.
Maida A, Zota A, Sjøberg KA, Schumacher J, Sijmonsma TP, Pfenninger A, Christensen MM, Gantert T, Fuhrmeister J, Rothermel U, Schmoll D, Heikenwälder M, Iovanna JL, Stemmer K, Kiens B, Herzig S, Rose AJ. Maida A, et al. Among authors: heikenwalder m. J Clin Invest. 2016 Sep 1;126(9):3263-78. doi: 10.1172/JCI85946. Epub 2016 Aug 22. J Clin Invest. 2016. PMID: 27548521 Free PMC article.
Chemical Hybridization of Glucagon and Thyroid Hormone Optimizes Therapeutic Impact for Metabolic Disease.
Finan B, Clemmensen C, Zhu Z, Stemmer K, Gauthier K, Müller L, De Angelis M, Moreth K, Neff F, Perez-Tilve D, Fischer K, Lutter D, Sánchez-Garrido MA, Liu P, Tuckermann J, Malehmir M, Healy ME, Weber A, Heikenwalder M, Jastroch M, Kleinert M, Jall S, Brandt S, Flamant F, Schramm KW, Biebermann H, Döring Y, Weber C, Habegger KM, Keuper M, Gelfanov V, Liu F, Köhrle J, Rozman J, Fuchs H, Gailus-Durner V, Hrabě de Angelis M, Hofmann SM, Yang B, Tschöp MH, DiMarchi R, Müller TD. Finan B, et al. Among authors: heikenwalder m. Cell. 2016 Oct 20;167(3):843-857.e14. doi: 10.1016/j.cell.2016.09.014. Epub 2016 Oct 6. Cell. 2016. PMID: 27720451 Free article.
Jak-TGFβ cross-talk links transient adipose tissue inflammation to beige adipogenesis.
Babaei R, Schuster M, Meln I, Lerch S, Ghandour RA, Pisani DF, Bayindir-Buchhalter I, Marx J, Wu S, Schoiswohl G, Billeter AT, Krunic D, Mauer J, Lee YH, Granneman JG, Fischer L, Müller-Stich BP, Amri EZ, Kershaw EE, Heikenwälder M, Herzig S, Vegiopoulos A. Babaei R, et al. Among authors: heikenwalder m. Sci Signal. 2018 Apr 24;11(527):eaai7838. doi: 10.1126/scisignal.aai7838. Sci Signal. 2018. PMID: 29692363
Diet-dependent function of the extracellular matrix proteoglycan Lumican in obesity and glucose homeostasis.
Wolff G, Taranko AE, Meln I, Weinmann J, Sijmonsma T, Lerch S, Heide D, Billeter AT, Tews D, Krunic D, Fischer-Posovszky P, Müller-Stich BP, Herzig S, Grimm D, Heikenwälder M, Kao WW, Vegiopoulos A. Wolff G, et al. Among authors: heikenwalder m. Mol Metab. 2019 Jan;19:97-106. doi: 10.1016/j.molmet.2018.10.007. Epub 2018 Oct 23. Mol Metab. 2019. PMID: 30409703 Free PMC article.
Platelet GPIbα is a mediator and potential interventional target for NASH and subsequent liver cancer.
Malehmir M, Pfister D, Gallage S, Szydlowska M, Inverso D, Kotsiliti E, Leone V, Peiseler M, Surewaard BGJ, Rath D, Ali A, Wolf MJ, Drescher H, Healy ME, Dauch D, Kroy D, Krenkel O, Kohlhepp M, Engleitner T, Olkus A, Sijmonsma T, Volz J, Deppermann C, Stegner D, Helbling P, Nombela-Arrieta C, Rafiei A, Hinterleitner M, Rall M, Baku F, Borst O, Wilson CL, Leslie J, O'Connor T, Weston CJ, Chauhan A, Adams DH, Sheriff L, Teijeiro A, Prinz M, Bogeska R, Anstee N, Bongers MN, Notohamiprodjo M, Geisler T, Withers DJ, Ware J, Mann DA, Augustin HG, Vegiopoulos A, Milsom MD, Rose AJ, Lalor PF, Llovet JM, Pinyol R, Tacke F, Rad R, Matter M, Djouder N, Kubes P, Knolle PA, Unger K, Zender L, Nieswandt B, Gawaz M, Weber A, Heikenwalder M. Malehmir M, et al. Among authors: heikenwalder m. Nat Med. 2019 Apr;25(4):641-655. doi: 10.1038/s41591-019-0379-5. Epub 2019 Apr 1. Nat Med. 2019. PMID: 30936549 Free article.
Liver alanine catabolism promotes skeletal muscle atrophy and hyperglycaemia in type 2 diabetes.
Okun JG, Rusu PM, Chan AY, Wu Y, Yap YW, Sharkie T, Schumacher J, Schmidt KV, Roberts-Thomson KM, Russell RD, Zota A, Hille S, Jungmann A, Maggi L, Lee Y, Blüher M, Herzig S, Keske MA, Heikenwalder M, Müller OJ, Rose AJ. Okun JG, et al. Among authors: heikenwalder m. Nat Metab. 2021 Mar;3(3):394-409. doi: 10.1038/s42255-021-00369-9. Epub 2021 Mar 18. Nat Metab. 2021. PMID: 33758419
329 results