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Effects of Prebiotics vs a Diet Low in FODMAPs in Patients With Functional Gut Disorders.
Huaman JW, Mego M, Manichanh C, Cañellas N, Cañueto D, Segurola H, Jansana M, Malagelada C, Accarino A, Vulevic J, Tzortzis G, Gibson G, Saperas E, Guarner F, Azpiroz F. Huaman JW, et al. Among authors: saperas e. Gastroenterology. 2018 Oct;155(4):1004-1007. doi: 10.1053/j.gastro.2018.06.045. Epub 2018 Jun 30. Gastroenterology. 2018. PMID: 29964041 Clinical Trial.
Chronic psychosocial stress induces reversible mitochondrial damage and corticotropin-releasing factor receptor type-1 upregulation in the rat intestine and IBS-like gut dysfunction.
Vicario M, Alonso C, Guilarte M, Serra J, Martínez C, González-Castro AM, Lobo B, Antolín M, Andreu AL, García-Arumí E, Casellas M, Saperas E, Malagelada JR, Azpiroz F, Santos J. Vicario M, et al. Among authors: saperas e. Psychoneuroendocrinology. 2012 Jan;37(1):65-77. doi: 10.1016/j.psyneuen.2011.05.005. Epub 2011 Jun 8. Psychoneuroendocrinology. 2012. PMID: 21641728
The jejunum of diarrhea-predominant irritable bowel syndrome shows molecular alterations in the tight junction signaling pathway that are associated with mucosal pathobiology and clinical manifestations.
Martínez C, Vicario M, Ramos L, Lobo B, Mosquera JL, Alonso C, Sánchez A, Guilarte M, Antolín M, de Torres I, González-Castro AM, Pigrau M, Saperas E, Azpiroz F, Santos J. Martínez C, et al. Among authors: saperas e. Am J Gastroenterol. 2012 May;107(5):736-46. doi: 10.1038/ajg.2011.472. Epub 2012 Mar 13. Am J Gastroenterol. 2012. PMID: 22415197
Correction of Dyssynergic Defecation, but Not Fiber Supplementation, Reduces Symptoms of Functional Dyspepsia in Patients With Constipation in a Randomized Trial.
Huaman JW, Mego M, Bendezú A, Monrroy H, Samino S, Accarino A, Saperas E, Azpiroz F. Huaman JW, et al. Among authors: saperas e. Clin Gastroenterol Hepatol. 2020 Oct;18(11):2463-2470.e1. doi: 10.1016/j.cgh.2019.11.048. Epub 2019 Dec 4. Clin Gastroenterol Hepatol. 2020. PMID: 31811952 Free article. Clinical Trial.
Peripheral Corticotropin-Releasing Factor Triggers Jejunal Mast Cell Activation and Abdominal Pain in Patients With Diarrhea-Predominant Irritable Bowel Syndrome.
Guilarte M, Vicario M, Martínez C, de Torres I, Lobo B, Pigrau M, González-Castro A, Rodiño-Janeiro BK, Salvo-Romero E, Fortea M, Pardo-Camacho C, Antolín M, Saperas E, Azpiroz F, Santos J, Alonso-Cotoner C. Guilarte M, et al. Among authors: saperas e. Am J Gastroenterol. 2020 Dec;115(12):2047-2059. doi: 10.14309/ajg.0000000000000789. Am J Gastroenterol. 2020. PMID: 32740086
Effectiveness of a high fiber diet in improving constipation in patients with defecatory dyssynergy under treatment with anorrectal biofeedback. Exploratory, randomized clinical trial.
Mego M, Huaman JW, Videla S, Jansana M, Tinoco K, Saperas E. Mego M, et al. Among authors: saperas e. Gastroenterol Hepatol. 2023 Dec;46(10):774-783. doi: 10.1016/j.gastrohep.2023.01.012. Epub 2023 Jan 31. Gastroenterol Hepatol. 2023. PMID: 36731727 Clinical Trial. English, Spanish.
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