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Decitabine induces regulatory T cells, inhibits the production of IFN-gamma and IL-17 and exerts preventive and therapeutic efficacy in rodent experimental autoimmune neuritis.
Fagone P, Mazzon E, Chikovani T, Saraceno A, Mammana S, Colletti G, Mangano K, Bramanti P, Nicoletti F. Fagone P, et al. Among authors: mangano k. J Neuroimmunol. 2018 Aug 15;321:41-48. doi: 10.1016/j.jneuroim.2018.05.013. Epub 2018 May 28. J Neuroimmunol. 2018. PMID: 29957387 Free article.
Activation of group III metabotropic glutamate receptors inhibits the production of RANTES in glial cell cultures.
Besong G, Battaglia G, D'Onofrio M, Di Marco R, Ngomba RT, Storto M, Castiglione M, Mangano K, Busceti CL, Nicoletti FR, Bacon K, Tusche M, Valenti O, Conn PJ, Bruno V, Nicoletti F. Besong G, et al. Among authors: mangano k. J Neurosci. 2002 Jul 1;22(13):5403-11. doi: 10.1523/JNEUROSCI.22-13-05403.2002. J Neurosci. 2002. PMID: 12097492 Free PMC article.
In vitro, ex vivo and in vivo immunopharmacological activities of the isoxazoline compound VGX-1027: modulation of cytokine synthesis and prevention of both organ-specific and systemic autoimmune diseases in murine models.
Stojanovic I, Cuzzocrea S, Mangano K, Mazzon E, Miljkovic D, Wang M, Donia M, Al Abed Y, Kim J, Nicoletti F, Stosic-Grujicic S, Claesson M. Stojanovic I, et al. Among authors: mangano k. Clin Immunol. 2007 Jun;123(3):311-23. doi: 10.1016/j.clim.2007.03.004. Epub 2007 Apr 20. Clin Immunol. 2007. PMID: 17449326
Anticancer properties of the novel nitric oxide-donating compound (S,R)-3-phenyl-4,5-dihydro-5-isoxazole acetic acid-nitric oxide in vitro and in vivo.
Maksimovic-Ivanic D, Mijatovic S, Harhaji L, Miljkovic D, Dabideen D, Fan Cheng K, Mangano K, Malaponte G, Al-Abed Y, Libra M, Garotta G, Nicoletti F, Stosic-Grujicic S. Maksimovic-Ivanic D, et al. Among authors: mangano k. Mol Cancer Ther. 2008 Mar;7(3):510-20. doi: 10.1158/1535-7163.MCT-07-2037. Mol Cancer Ther. 2008. PMID: 18347138
163 results