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Page 1
Toxicity of aerosols of nicotine and pyruvic acid (separate and combined) in Sprague-Dawley rats in a 28-day OECD 412 inhalation study and assessment of systems toxicology.
Phillips B, Esposito M, Verbeeck J, Boué S, Iskandar A, Vuillaume G, Leroy P, Krishnan S, Kogel U, Utan A, Schlage WK, Bera M, Veljkovic E, Hoeng J, Peitsch MC, Vanscheeuwijck P. Phillips B, et al. Among authors: schlage wk. Inhal Toxicol. 2015;27(9):405-31. doi: 10.3109/08958378.2015.1046000. Epub 2015 Aug 20. Inhal Toxicol. 2015. PMID: 26295358
Toxicity of the main electronic cigarette components, propylene glycol, glycerin, and nicotine, in Sprague-Dawley rats in a 90-day OECD inhalation study complemented by molecular endpoints.
Phillips B, Titz B, Kogel U, Sharma D, Leroy P, Xiang Y, Vuillaume G, Lebrun S, Sciuscio D, Ho J, Nury C, Guedj E, Elamin A, Esposito M, Krishnan S, Schlage WK, Veljkovic E, Ivanov NV, Martin F, Peitsch MC, Hoeng J, Vanscheeuwijck P. Phillips B, et al. Among authors: schlage wk. Food Chem Toxicol. 2017 Nov;109(Pt 1):315-332. doi: 10.1016/j.fct.2017.09.001. Epub 2017 Sep 5. Food Chem Toxicol. 2017. PMID: 28882640 Free article.
A 6-month systems toxicology inhalation study in ApoE-/- mice demonstrates reduced cardiovascular effects of E-vapor aerosols compared with cigarette smoke.
Szostak J, Wong ET, Titz B, Lee T, Wong SK, Low T, Lee KM, Zhang J, Kumar A, Schlage WK, Guedj E, Phillips B, Leroy P, Buettner A, Xiang Y, Martin F, Sewer A, Kuczaj A, Ivanov NV, Luettich K, Vanscheeuwijck P, Peitsch MC, Hoeng J. Szostak J, et al. Among authors: schlage wk. Am J Physiol Heart Circ Physiol. 2020 Mar 1;318(3):H604-H631. doi: 10.1152/ajpheart.00613.2019. Epub 2020 Jan 24. Am J Physiol Heart Circ Physiol. 2020. PMID: 31975625 Free article.
Impact of whole-body versus nose-only inhalation exposure systems on systemic, respiratory, and cardiovascular endpoints in a 2-month cigarette smoke exposure study in the ApoE-/- mouse model.
Kogel U, Wong ET, Szostak J, Tan WT, Lucci F, Leroy P, Titz B, Xiang Y, Low T, Wong SK, Guedj E, Ivanov NV, Schlage WK, Peitsch MC, Kuczaj A, Vanscheeuwijck P, Hoeng J. Kogel U, et al. Among authors: schlage wk. J Appl Toxicol. 2021 Oct;41(10):1598-1619. doi: 10.1002/jat.4149. Epub 2021 Apr 6. J Appl Toxicol. 2021. PMID: 33825214 Free PMC article.
A 6-month inhalation toxicology study in Apoe-/- mice demonstrates substantially lower effects of e-vapor aerosol compared with cigarette smoke in the respiratory tract.
Wong ET, Szostak J, Titz B, Lee T, Wong SK, Lavrynenko O, Merg C, Corciulo M, Simicevic J, Auberson M, Peric D, Dulize R, Bornand D, Loh GJ, Lee KM, Zhang J, Miller JH 4th, Schlage WK, Guedj E, Schneider T, Phillips B, Leroy P, Choukrallah MA, Sierro N, Buettner A, Xiang Y, Kuczaj A, Ivanov NV, Luettich K, Vanscheeuwijck P, Peitsch MC, Hoeng J. Wong ET, et al. Among authors: schlage wk. Arch Toxicol. 2021 May;95(5):1805-1829. doi: 10.1007/s00204-021-03020-4. Epub 2021 May 7. Arch Toxicol. 2021. PMID: 33963423 Free PMC article.
Cigarette smoke induces molecular responses in respiratory tissues of ApoE(-/-) mice that are progressively deactivated upon cessation.
Boué S, De León H, Schlage WK, Peck MJ, Weiler H, Berges A, Vuillaume G, Martin F, Friedrichs B, Lebrun S, Meurrens K, Schracke N, Moehring M, Steffen Y, Schueller J, Vanscheeuwijck P, Peitsch MC, Hoeng J. Boué S, et al. Among authors: schlage wk. Toxicology. 2013 Dec 6;314(1):112-24. doi: 10.1016/j.tox.2013.09.013. Epub 2013 Oct 1. Toxicology. 2013. PMID: 24096154 Free article.
Comparative biological impacts of an aerosol from carbon-heated tobacco and smoke from cigarettes on human respiratory epithelial cultures: A systems toxicology assessment.
Iskandar AR, Martin F, Leroy P, Schlage WK, Mathis C, Titz B, Kondylis A, Schneider T, Vuillaume G, Sewer A, Guedj E, Trivedi K, Elamin A, Frentzel S, Ivanov NV, Peitsch MC, Hoeng J. Iskandar AR, et al. Among authors: schlage wk. Food Chem Toxicol. 2018 May;115:109-126. doi: 10.1016/j.fct.2018.02.063. Epub 2018 Mar 1. Food Chem Toxicol. 2018. PMID: 29501877 Free article.
Assessment of the impact of aerosol from a potential modified risk tobacco product compared with cigarette smoke on human organotypic oral epithelial cultures under different exposure regimens.
Zanetti F, Sewer A, Scotti E, Titz B, Schlage WK, Leroy P, Kondylis A, Vuillaume G, Iskandar AR, Guedj E, Trivedi K, Schneider T, Elamin A, Martin F, Frentzel S, Ivanov NV, Peitsch MC, Hoeng J. Zanetti F, et al. Among authors: schlage wk. Food Chem Toxicol. 2018 May;115:148-169. doi: 10.1016/j.fct.2018.02.062. Epub 2018 Mar 2. Food Chem Toxicol. 2018. PMID: 29505817 Free article.
70 results