Pianowski LF - Search Results

1

Euphol, a tetracyclic triterpene, from Euphorbia tirucalli induces autophagy and sensitizes temozolomide cytotoxicity on glioblastoma cells.

Silva VAO, Rosa MN, Miranda-Gonçalves V, Costa AM, Tansini A, Evangelista AF, Martinho O, Carloni AC, Jones C, Lima JP, Pianowski LF, Reis RM. Silva VAO, et al. Among authors: pianowski lf. Invest New Drugs. 2019 Apr;37(2):223-237. doi: 10.1007/s10637-018-0620-y. Epub 2018 Jun 22. Invest New Drugs. 2019. PMID: 29931585

2

Semi-Synthetic Ingenol Derivative from Euphorbia tirucalli Inhibits Protein Kinase C Isotypes and Promotes Autophagy and S-phase Arrest on Glioma Cell Lines.

Silva VAO, Rosa MN, Tansini A, Martinho O, Tanuri A, Evangelista AF, Cruvinel Carloni A, Lima JP, Pianowski LF, Reis RM. Silva VAO, et al. Among authors: pianowski lf. Molecules. 2019 Nov 22;24(23):4265. doi: 10.3390/molecules24234265. Molecules. 2019. PMID: 31771098 Free PMC article.

3

Modified ingenol semi-synthetic derivatives from Euphorbia tirucalli induce cytotoxicity on a large panel of human cancer cell lines.

Silva VAO, Rosa MN, Martinho O, Tanuri A, Lima JP, Pianowski LF, Reis RM. Silva VAO, et al. Among authors: pianowski lf. Invest New Drugs. 2019 Oct;37(5):1029-1035. doi: 10.1007/s10637-019-00728-0. Epub 2019 Feb 1. Invest New Drugs. 2019. PMID: 30706338

4

In vitro screening of cytotoxic activity of euphol from Euphorbia tirucalli on a large panel of human cancer-derived cell lines.

Silva VAO, Rosa MN, Tansini A, Oliveira RJS, Martinho O, Lima JP, Pianowski LF, Reis RM. Silva VAO, et al. Among authors: pianowski lf. Exp Ther Med. 2018 Aug;16(2):557-566. doi: 10.3892/etm.2018.6244. Epub 2018 May 31. Exp Ther Med. 2018. PMID: 30112023 Free PMC article.

5

The antinociceptive effects of the tetracyclic triterpene euphol in inflammatory and neuropathic pain models: The potential role of PKCε.

Dutra RC, Bicca MA, Segat GC, Silva KA, Motta EM, Pianowski LF, Costa R, Calixto JB. Dutra RC, et al. Among authors: pianowski lf. Neuroscience. 2015 Sep 10;303:126-37. doi: 10.1016/j.neuroscience.2015.06.051. Epub 2015 Jul 2. Neuroscience. 2015. PMID: 26143011

6

The role of PKC/ERK1/2 signaling in the anti-inflammatory effect of tetracyclic triterpene euphol on TPA-induced skin inflammation in mice.

Passos GF, Medeiros R, Marcon R, Nascimento AF, Calixto JB, Pianowski LF. Passos GF, et al. Among authors: pianowski lf. Eur J Pharmacol. 2013 Jan 5;698(1-3):413-20. doi: 10.1016/j.ejphar.2012.10.019. Epub 2012 Oct 23. Eur J Pharmacol. 2013. PMID: 23099255 Free article.

7

Preventive and therapeutic euphol treatment attenuates experimental colitis in mice.

Dutra RC, Claudino RF, Bento AF, Marcon R, Schmidt EC, Bouzon ZL, Pianowski LF, Calixto JB. Dutra RC, et al. Among authors: pianowski lf. PLoS One. 2011;6(11):e27122. doi: 10.1371/journal.pone.0027122. Epub 2011 Nov 2. PLoS One. 2011. PMID: 22073270 Free PMC article.

8

Euphol, a tetracyclic triterpene produces antinociceptive effects in inflammatory and neuropathic pain: the involvement of cannabinoid system.

Dutra RC, Simão da Silva KA, Bento AF, Marcon R, Paszcuk AF, Meotti FC, Pianowski LF, Calixto JB. Dutra RC, et al. Among authors: pianowski lf. Neuropharmacology. 2012 Sep;63(4):593-605. doi: 10.1016/j.neuropharm.2012.05.008. Epub 2012 May 18. Neuropharmacology. 2012. PMID: 22613837

9

Dual role of novel ingenol derivatives from Euphorbia tirucalli in HIV replication: inhibition of de novo infection and activation of viral LTR.

Abreu CM, Price SL, Shirk EN, Cunha RD, Pianowski LF, Clements JE, Tanuri A, Gama L. Abreu CM, et al. Among authors: pianowski lf. PLoS One. 2014 May 14;9(5):e97257. doi: 10.1371/journal.pone.0097257. eCollection 2014. PLoS One. 2014. PMID: 24827152 Free PMC article.

10

Euphol prevents experimental autoimmune encephalomyelitis in mice: evidence for the underlying mechanisms.

Dutra RC, de Souza PR, Bento AF, Marcon R, Bicca MA, Pianowski LF, Calixto JB. Dutra RC, et al. Among authors: pianowski lf. Biochem Pharmacol. 2012 Feb 15;83(4):531-42. doi: 10.1016/j.bcp.2011.11.026. Epub 2011 Dec 1. Biochem Pharmacol. 2012. PMID: 22155310

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