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Afatinib restrains K-RAS-driven lung tumorigenesis.
Moll HP, Pranz K, Musteanu M, Grabner B, Hruschka N, Mohrherr J, Aigner P, Stiedl P, Brcic L, Laszlo V, Schramek D, Moriggl R, Eferl R, Moldvay J, Dezso K, Lopez-Casas PP, Stoiber D, Hidalgo M, Penninger J, Sibilia M, Győrffy B, Barbacid M, Dome B, Popper H, Casanova E. Moll HP, et al. Among authors: schramek d. Sci Transl Med. 2018 Jun 20;10(446):eaao2301. doi: 10.1126/scitranslmed.aao2301. Sci Transl Med. 2018. PMID: 29925635 Free PMC article.
Genome-wide RNAi screen identifies genes involved in intestinal pathogenic bacterial infection.
Cronin SJ, Nehme NT, Limmer S, Liegeois S, Pospisilik JA, Schramek D, Leibbrandt A, Simoes Rde M, Gruber S, Puc U, Ebersberger I, Zoranovic T, Neely GG, von Haeseler A, Ferrandon D, Penninger JM. Cronin SJ, et al. Among authors: schramek d. Science. 2009 Jul 17;325(5938):340-3. doi: 10.1126/science.1173164. Epub 2009 Jun 11. Science. 2009. PMID: 19520911 Free PMC article.
Disruption of the growth hormone--signal transducer and activator of transcription 5--insulinlike growth factor 1 axis severely aggravates liver fibrosis in a mouse model of cholestasis.
Blaas L, Kornfeld JW, Schramek D, Musteanu M, Zollner G, Gumhold J, van Zijl F, Schneller D, Esterbauer H, Egger G, Mair M, Kenner L, Mikulits W, Eferl R, Moriggl R, Penninger J, Trauner M, Casanova E. Blaas L, et al. Among authors: schramek d. Hepatology. 2010 Apr;51(4):1319-26. doi: 10.1002/hep.23469. Hepatology. 2010. PMID: 20162728 Free PMC article.
RANKL/RANK-beyond bones.
Hanada R, Hanada T, Sigl V, Schramek D, Penninger JM. Hanada R, et al. Among authors: schramek d. J Mol Med (Berl). 2011 Jul;89(7):647-56. doi: 10.1007/s00109-011-0749-z. Epub 2011 Mar 29. J Mol Med (Berl). 2011. PMID: 21445556 Review.
Forward and reverse genetics through derivation of haploid mouse embryonic stem cells.
Elling U, Taubenschmid J, Wirnsberger G, O'Malley R, Demers SP, Vanhaelen Q, Shukalyuk AI, Schmauss G, Schramek D, Schnuetgen F, von Melchner H, Ecker JR, Stanford WL, Zuber J, Stark A, Penninger JM. Elling U, et al. Among authors: schramek d. Cell Stem Cell. 2011 Dec 2;9(6):563-74. doi: 10.1016/j.stem.2011.10.012. Cell Stem Cell. 2011. PMID: 22136931 Free PMC article.
A mouse model to identify cooperating signaling pathways in cancer.
Musteanu M, Blaas L, Zenz R, Svinka J, Hoffmann T, Grabner B, Schramek D, Kantner HP, Müller M, Kolbe T, Rülicke T, Moriggl R, Kenner L, Stoiber D, Penninger JM, Popper H, Casanova E, Eferl R. Musteanu M, et al. Among authors: schramek d. Nat Methods. 2012 Sep;9(9):897-900. doi: 10.1038/nmeth.2130. Epub 2012 Aug 5. Nat Methods. 2012. PMID: 22863881
Disruption of STAT3 signalling promotes KRAS-induced lung tumorigenesis.
Grabner B, Schramek D, Mueller KM, Moll HP, Svinka J, Hoffmann T, Bauer E, Blaas L, Hruschka N, Zboray K, Stiedl P, Nivarthi H, Bogner E, Gruber W, Mohr T, Zwick RH, Kenner L, Poli V, Aberger F, Stoiber D, Egger G, Esterbauer H, Zuber J, Moriggl R, Eferl R, Győrffy B, Penninger JM, Popper H, Casanova E. Grabner B, et al. Among authors: schramek d. Nat Commun. 2015 Mar 3;6:6285. doi: 10.1038/ncomms7285. Nat Commun. 2015. PMID: 25734337 Free PMC article.
67 results