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Evolution and Diversity of Biosynthetic Gene Clusters in Fusarium.
Hoogendoorn K, Barra L, Waalwijk C, Dickschat JS, van der Lee TAJ, Medema MH. Hoogendoorn K, et al. Among authors: medema mh. Front Microbiol. 2018 Jun 5;9:1158. doi: 10.3389/fmicb.2018.01158. eCollection 2018. Front Microbiol. 2018. PMID: 29922257 Free PMC article.
Towards the sustainable discovery and development of new antibiotics.
Miethke M, Pieroni M, Weber T, Brönstrup M, Hammann P, Halby L, Arimondo PB, Glaser P, Aigle B, Bode HB, Moreira R, Li Y, Luzhetskyy A, Medema MH, Pernodet JL, Stadler M, Tormo JR, Genilloud O, Truman AW, Weissman KJ, Takano E, Sabatini S, Stegmann E, Brötz-Oesterhelt H, Wohlleben W, Seemann M, Empting M, Hirsch AKH, Loretz B, Lehr CM, Titz A, Herrmann J, Jaeger T, Alt S, Hesterkamp T, Winterhalter M, Schiefer A, Pfarr K, Hoerauf A, Graz H, Graz M, Lindvall M, Ramurthy S, Karlén A, van Dongen M, Petkovic H, Keller A, Peyrane F, Donadio S, Fraisse L, Piddock LJV, Gilbert IH, Moser HE, Müller R. Miethke M, et al. Among authors: medema mh. Nat Rev Chem. 2021 Oct;5(10):726-749. doi: 10.1038/s41570-021-00313-1. Epub 2021 Aug 19. Nat Rev Chem. 2021. PMID: 37118182 Review.
Total Synthesis and Structure Assignment of the Relacidine Lipopeptide Antibiotics and Preparation of Analogues with Enhanced Stability.
Al Ayed K, Zamarbide Losada D, Machushynets NV, Terlouw B, Elsayed SS, Schill J, Trebosc V, Pieren M, Medema MH, van Wezel GP, Martin NI. Al Ayed K, et al. Among authors: medema mh. ACS Infect Dis. 2023 Apr 14;9(4):739-748. doi: 10.1021/acsinfecdis.3c00043. Epub 2023 Mar 31. ACS Infect Dis. 2023. PMID: 37000899 Free PMC article.
antiSMASH 4.0-improvements in chemistry prediction and gene cluster boundary identification.
Blin K, Wolf T, Chevrette MG, Lu X, Schwalen CJ, Kautsar SA, Suarez Duran HG, de Los Santos ELC, Kim HU, Nave M, Dickschat JS, Mitchell DA, Shelest E, Breitling R, Takano E, Lee SY, Weber T, Medema MH. Blin K, et al. Among authors: medema mh. Nucleic Acids Res. 2017 Jul 3;45(W1):W36-W41. doi: 10.1093/nar/gkx319. Nucleic Acids Res. 2017. PMID: 28460038 Free PMC article.
luxR Homolog-Linked Biosynthetic Gene Clusters in Proteobacteria.
Brotherton CA, Medema MH, Greenberg EP. Brotherton CA, et al. Among authors: medema mh. mSystems. 2018 Mar 27;3(3):e00208-17. doi: 10.1128/mSystems.00208-17. eCollection 2018 May-Jun. mSystems. 2018. PMID: 29600287 Free PMC article.
Comprehensive curation and analysis of fungal biosynthetic gene clusters of published natural products.
Li YF, Tsai KJS, Harvey CJB, Li JJ, Ary BE, Berlew EE, Boehman BL, Findley DM, Friant AG, Gardner CA, Gould MP, Ha JH, Lilley BK, McKinstry EL, Nawal S, Parry RC, Rothchild KW, Silbert SD, Tentilucci MD, Thurston AM, Wai RB, Yoon Y, Aiyar RS, Medema MH, Hillenmeyer ME, Charkoudian LK. Li YF, et al. Among authors: medema mh. Fungal Genet Biol. 2016 Apr;89:18-28. doi: 10.1016/j.fgb.2016.01.012. Epub 2016 Jan 22. Fungal Genet Biol. 2016. PMID: 26808821 Free PMC article.
149 results