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Modulating Protein Phosphatase 2A Rescues Disease Phenotype in Neurodegenerative Tauopathies.
McKenzie-Nickson S, Chan J, Perez K, Hung LW, Cheng L, Sedjahtera A, Gunawan L, Adlard PA, Hayne DJ, McInnes LE, Donnelly PS, Finkelstein DI, Hill AF, Barnham KJ. McKenzie-Nickson S, et al. Among authors: finkelstein di. ACS Chem Neurosci. 2018 Nov 21;9(11):2731-2740. doi: 10.1021/acschemneuro.8b00161. Epub 2018 Jul 3. ACS Chem Neurosci. 2018. PMID: 29920069
Rapid restoration of cognition in Alzheimer's transgenic mice with 8-hydroxy quinoline analogs is associated with decreased interstitial Abeta.
Adlard PA, Cherny RA, Finkelstein DI, Gautier E, Robb E, Cortes M, Volitakis I, Liu X, Smith JP, Perez K, Laughton K, Li QX, Charman SA, Nicolazzo JA, Wilkins S, Deleva K, Lynch T, Kok G, Ritchie CW, Tanzi RE, Cappai R, Masters CL, Barnham KJ, Bush AI. Adlard PA, et al. Among authors: finkelstein di. Neuron. 2008 Jul 10;59(1):43-55. doi: 10.1016/j.neuron.2008.06.018. Neuron. 2008. PMID: 18614028 Free article.
Tau protein: relevance to Parkinson's disease.
Lei P, Ayton S, Finkelstein DI, Adlard PA, Masters CL, Bush AI. Lei P, et al. Among authors: finkelstein di. Int J Biochem Cell Biol. 2010 Nov;42(11):1775-8. doi: 10.1016/j.biocel.2010.07.016. Epub 2010 Aug 1. Int J Biochem Cell Biol. 2010. PMID: 20678581 Review.
Diacetylbis(N(4)-methylthiosemicarbazonato) copper(II) (CuII(atsm)) protects against peroxynitrite-induced nitrosative damage and prolongs survival in amyotrophic lateral sclerosis mouse model.
Soon CPW, Donnelly PS, Turner BJ, Hung LW, Crouch PJ, Sherratt NA, Tan JL, Lim NK, Lam L, Bica L, Lim S, Hickey JL, Morizzi J, Powell A, Finkelstein DI, Culvenor JG, Masters CL, Duce J, White AR, Barnham KJ, Li QX. Soon CPW, et al. Among authors: finkelstein di. J Biol Chem. 2011 Dec 23;286(51):44035-44044. doi: 10.1074/jbc.M111.274407. Epub 2011 Oct 27. J Biol Chem. 2011. PMID: 22033929 Free PMC article.
The hypoxia imaging agent CuII(atsm) is neuroprotective and improves motor and cognitive functions in multiple animal models of Parkinson's disease.
Hung LW, Villemagne VL, Cheng L, Sherratt NA, Ayton S, White AR, Crouch PJ, Lim S, Leong SL, Wilkins S, George J, Roberts BR, Pham CL, Liu X, Chiu FC, Shackleford DM, Powell AK, Masters CL, Bush AI, O'Keefe G, Culvenor JG, Cappai R, Cherny RA, Donnelly PS, Hill AF, Finkelstein DI, Barnham KJ. Hung LW, et al. Among authors: finkelstein di. J Exp Med. 2012 Apr 9;209(4):837-54. doi: 10.1084/jem.20112285. Epub 2012 Apr 2. J Exp Med. 2012. PMID: 22473957 Free PMC article.
199 results