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Evolution of New Delhi metallo-β-lactamase (NDM) in the clinic: Effects of NDM mutations on stability, zinc affinity, and mono-zinc activity.
Cheng Z, Thomas PW, Ju L, Bergstrom A, Mason K, Clayton D, Miller C, Bethel CR, VanPelt J, Tierney DL, Page RC, Bonomo RA, Fast W, Crowder MW. Cheng Z, et al. Among authors: tierney dl. J Biol Chem. 2018 Aug 10;293(32):12606-12618. doi: 10.1074/jbc.RA118.003835. Epub 2018 Jun 16. J Biol Chem. 2018. PMID: 29909397 Free PMC article.
A five-coordinate metal center in Co(II)-substituted VanX.
Breece RM, Costello A, Bennett B, Sigdel TK, Matthews ML, Tierney DL, Crowder MW. Breece RM, et al. Among authors: tierney dl. J Biol Chem. 2005 Mar 25;280(12):11074-81. doi: 10.1074/jbc.M412582200. Epub 2005 Jan 17. J Biol Chem. 2005. PMID: 15657055 Free article.
The metallo-beta-lactamase GOB is a mono-Zn(II) enzyme with a novel active site.
Morán-Barrio J, González JM, Lisa MN, Costello AL, Peraro MD, Carloni P, Bennett B, Tierney DL, Limansky AS, Viale AM, Vila AJ. Morán-Barrio J, et al. Among authors: tierney dl. J Biol Chem. 2007 Jun 22;282(25):18286-18293. doi: 10.1074/jbc.M700467200. Epub 2007 Apr 2. J Biol Chem. 2007. PMID: 17403673 Free article.
85 results