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Nrf2 Deficiency Exacerbates Obesity-Induced Oxidative Stress, Neurovascular Dysfunction, Blood-Brain Barrier Disruption, Neuroinflammation, Amyloidogenic Gene Expression, and Cognitive Decline in Mice, Mimicking the Aging Phenotype.
Tarantini S, Valcarcel-Ares MN, Yabluchanskiy A, Tucsek Z, Hertelendy P, Kiss T, Gautam T, Zhang XA, Sonntag WE, de Cabo R, Farkas E, Elliott MH, Kinter MT, Deak F, Ungvari Z, Csiszar A. Tarantini S, et al. Among authors: deak f. J Gerontol A Biol Sci Med Sci. 2018 Jun 14;73(7):853-863. doi: 10.1093/gerona/glx177. J Gerontol A Biol Sci Med Sci. 2018. PMID: 29905772 Free PMC article.
Synergistic effects of hypertension and aging on cognitive function and hippocampal expression of genes involved in β-amyloid generation and Alzheimer's disease.
Csiszar A, Tucsek Z, Toth P, Sosnowska D, Gautam T, Koller A, Deak F, Sonntag WE, Ungvari Z. Csiszar A, et al. Among authors: deak f. Am J Physiol Heart Circ Physiol. 2013 Oct 15;305(8):H1120-30. doi: 10.1152/ajpheart.00288.2013. Epub 2013 Aug 16. Am J Physiol Heart Circ Physiol. 2013. PMID: 23955715 Free PMC article.
Pharmacologically-induced neurovascular uncoupling is associated with cognitive impairment in mice.
Tarantini S, Hertelendy P, Tucsek Z, Valcarcel-Ares MN, Smith N, Menyhart A, Farkas E, Hodges EL, Towner R, Deak F, Sonntag WE, Csiszar A, Ungvari Z, Toth P. Tarantini S, et al. Among authors: deak f. J Cereb Blood Flow Metab. 2015 Nov;35(11):1871-81. doi: 10.1038/jcbfm.2015.162. Epub 2015 Jul 15. J Cereb Blood Flow Metab. 2015. PMID: 26174328 Free PMC article.
Obesity in Aging Exacerbates Neuroinflammation, Dysregulating Synaptic Function-Related Genes and Altering Eicosanoid Synthesis in the Mouse Hippocampus: Potential Role in Impaired Synaptic Plasticity and Cognitive Decline.
Valcarcel-Ares MN, Tucsek Z, Kiss T, Giles CB, Tarantini S, Yabluchanskiy A, Balasubramanian P, Gautam T, Galvan V, Ballabh P, Richardson A, Freeman WM, Wren JD, Deak F, Ungvari Z, Csiszar A. Valcarcel-Ares MN, et al. Among authors: deak f. J Gerontol A Biol Sci Med Sci. 2019 Feb 15;74(3):290-298. doi: 10.1093/gerona/gly127. J Gerontol A Biol Sci Med Sci. 2019. PMID: 29893815 Free PMC article.
Ionizing radiation promotes the acquisition of a senescence-associated secretory phenotype and impairs angiogenic capacity in cerebromicrovascular endothelial cells: role of increased DNA damage and decreased DNA repair capacity in microvascular radiosensitivity.
Ungvari Z, Podlutsky A, Sosnowska D, Tucsek Z, Toth P, Deak F, Gautam T, Csiszar A, Sonntag WE. Ungvari Z, et al. Among authors: deak f. J Gerontol A Biol Sci Med Sci. 2013 Dec;68(12):1443-57. doi: 10.1093/gerona/glt057. Epub 2013 May 20. J Gerontol A Biol Sci Med Sci. 2013. PMID: 23689827 Free PMC article.
Insulin-like growth factor-1 in CNS and cerebrovascular aging.
Sonntag WE, Deak F, Ashpole N, Toth P, Csiszar A, Freeman W, Ungvari Z. Sonntag WE, et al. Among authors: deak f. Front Aging Neurosci. 2013 Jul 2;5:27. doi: 10.3389/fnagi.2013.00027. eCollection 2013. Front Aging Neurosci. 2013. PMID: 23847531 Free PMC article.
Hypertension-induced synapse loss and impairment in synaptic plasticity in the mouse hippocampus mimics the aging phenotype: implications for the pathogenesis of vascular cognitive impairment.
Tucsek Z, Noa Valcarcel-Ares M, Tarantini S, Yabluchanskiy A, Fülöp G, Gautam T, Orock A, Csiszar A, Deak F, Ungvari Z. Tucsek Z, et al. Among authors: deak f. Geroscience. 2017 Aug;39(4):385-406. doi: 10.1007/s11357-017-9981-y. Epub 2017 Jun 29. Geroscience. 2017. PMID: 28664509 Free PMC article.
128 results