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Heparins increase endothelial nitric oxide bioavailability by liberating vessel-immobilized myeloperoxidase.
Baldus S, Rudolph V, Roiss M, Ito WD, Rudolph TK, Eiserich JP, Sydow K, Lau D, Szöcs K, Klinke A, Kubala L, Berglund L, Schrepfer S, Deuse T, Haddad M, Risius T, Klemm H, Reichenspurner HC, Meinertz T, Heitzer T. Baldus S, et al. Among authors: kubala l. Circulation. 2006 Apr 18;113(15):1871-8. doi: 10.1161/CIRCULATIONAHA.105.590083. Epub 2006 Apr 10. Circulation. 2006. PMID: 16606792
Myeloperoxidase attracts neutrophils by physical forces.
Klinke A, Nussbaum C, Kubala L, Friedrichs K, Rudolph TK, Rudolph V, Paust HJ, Schröder C, Benten D, Lau D, Szocs K, Furtmüller PG, Heeringa P, Sydow K, Duchstein HJ, Ehmke H, Schumacher U, Meinertz T, Sperandio M, Baldus S. Klinke A, et al. Among authors: kubala l. Blood. 2011 Jan 27;117(4):1350-8. doi: 10.1182/blood-2010-05-284513. Epub 2010 Oct 27. Blood. 2011. PMID: 20980678 Free article.
Pathogenic cycle between the endogenous nitric oxide synthase inhibitor asymmetrical dimethylarginine and the leukocyte-derived hemoprotein myeloperoxidase.
von Leitner EC, Klinke A, Atzler D, Slocum JL, Lund N, Kielstein JT, Maas R, Schmidt-Haupt R, Pekarova M, Hellwinkel O, Tsikas D, D'Alecy LG, Lau D, Willems S, Kubala L, Ehmke H, Meinertz T, Blankenberg S, Schwedhelm E, Gadegbeku CA, Böger RH, Baldus S, Sydow K. von Leitner EC, et al. Among authors: kubala l. Circulation. 2011 Dec 13;124(24):2735-45. doi: 10.1161/CIRCULATIONAHA.111.060541. Epub 2011 Nov 14. Circulation. 2011. PMID: 22082678
154 results