Dawson R - Search Results

1

Structure of the µ-opioid receptor-G_i protein complex.

Koehl A, Hu H, Maeda S, Zhang Y, Qu Q, Paggi JM, Latorraca NR, Hilger D, Dawson R, Matile H, Schertler GFX, Granier S, Weis WI, Dror RO, Manglik A, Skiniotis G, Kobilka BK. Koehl A, et al. Among authors: dawson r. Nature. 2018 Jun;558(7711):547-552. doi: 10.1038/s41586-018-0219-7. Epub 2018 Jun 13. Nature. 2018. PMID: 29899455 Free PMC article.

2

Probing Gαi1 protein activation at single-amino acid resolution.

Sun D, Flock T, Deupi X, Maeda S, Matkovic M, Mendieta S, Mayer D, Dawson R, Schertler GFX, Madan Babu M, Veprintsev DB. Sun D, et al. Among authors: dawson r. Nat Struct Mol Biol. 2015 Sep;22(9):686-694. doi: 10.1038/nsmb.3070. Epub 2015 Aug 10. Nat Struct Mol Biol. 2015. PMID: 26258638 Free PMC article.

3

Development of an antibody fragment that stabilizes GPCR/G-protein complexes.

Maeda S, Koehl A, Matile H, Hu H, Hilger D, Schertler GFX, Manglik A, Skiniotis G, Dawson RJP, Kobilka BK. Maeda S, et al. Nat Commun. 2018 Sep 13;9(1):3712. doi: 10.1038/s41467-018-06002-w. Nat Commun. 2018. PMID: 30213947 Free PMC article.

4

Cryo-EM structure of the rhodopsin-Gαi-βγ complex reveals binding of the rhodopsin C-terminal tail to the gβ subunit.

Tsai CJ, Marino J, Adaixo R, Pamula F, Muehle J, Maeda S, Flock T, Taylor NM, Mohammed I, Matile H, Dawson RJ, Deupi X, Stahlberg H, Schertler G. Tsai CJ, et al. Among authors: dawson rj. Elife. 2019 Jun 28;8:e46041. doi: 10.7554/eLife.46041. Elife. 2019. PMID: 31251171 Free PMC article.

5

Crystallization scale preparation of a stable GPCR signaling complex between constitutively active rhodopsin and G-protein.

Maeda S, Sun D, Singhal A, Foggetta M, Schmid G, Standfuss J, Hennig M, Dawson RJ, Veprintsev DB, Schertler GF. Maeda S, et al. PLoS One. 2014 Jun 30;9(6):e98714. doi: 10.1371/journal.pone.0098714. eCollection 2014. PLoS One. 2014. PMID: 24979345 Free PMC article.

6

Ligand channel in pharmacologically stabilized rhodopsin.

Mattle D, Kuhn B, Aebi J, Bedoucha M, Kekilli D, Grozinger N, Alker A, Rudolph MG, Schmid G, Schertler GFX, Hennig M, Standfuss J, Dawson RJP. Mattle D, et al. Proc Natl Acad Sci U S A. 2018 Apr 3;115(14):3640-3645. doi: 10.1073/pnas.1718084115. Epub 2018 Mar 19. Proc Natl Acad Sci U S A. 2018. PMID: 29555765 Free PMC article.

7

Structure of a bacterial multidrug ABC transporter.

Dawson RJ, Locher KP. Dawson RJ, et al. Nature. 2006 Sep 14;443(7108):180-5. doi: 10.1038/nature05155. Epub 2006 Aug 30. Nature. 2006. PMID: 16943773

8

Structure of the acid-sensing ion channel 1 in complex with the gating modifier Psalmotoxin 1.

Dawson RJ, Benz J, Stohler P, Tetaz T, Joseph C, Huber S, Schmid G, Hügin D, Pflimlin P, Trube G, Rudolph MG, Hennig M, Ruf A. Dawson RJ, et al. Nat Commun. 2012 Jul 3;3:936. doi: 10.1038/ncomms1917. Nat Commun. 2012. PMID: 22760635 Free article.

9

Structural insights into the inhibition of glycine reuptake.

Shahsavar A, Stohler P, Bourenkov G, Zimmermann I, Siegrist M, Guba W, Pinard E, Sinning S, Seeger MA, Schneider TR, Dawson RJP, Nissen P. Shahsavar A, et al. Among authors: dawson rjp. Nature. 2021 Mar;591(7851):677-681. doi: 10.1038/s41586-021-03274-z. Epub 2021 Mar 3. Nature. 2021. PMID: 33658720

10

Structural Basis for Allosteric Ligand Recognition in the Human CC Chemokine Receptor 7.

Jaeger K, Bruenle S, Weinert T, Guba W, Muehle J, Miyazaki T, Weber M, Furrer A, Haenggi N, Tetaz T, Huang CY, Mattle D, Vonach JM, Gast A, Kuglstatter A, Rudolph MG, Nogly P, Benz J, Dawson RJP, Standfuss J. Jaeger K, et al. Cell. 2019 Aug 22;178(5):1222-1230.e10. doi: 10.1016/j.cell.2019.07.028. Cell. 2019. PMID: 31442409 Free PMC article.

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