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A disordered acidic domain in GPIHBP1 harboring a sulfated tyrosine regulates lipoprotein lipase.
Kristensen KK, Midtgaard SR, Mysling S, Kovrov O, Hansen LB, Skar-Gislinge N, Beigneux AP, Kragelund BB, Olivecrona G, Young SG, Jørgensen TJD, Fong LG, Ploug M. Kristensen KK, et al. Among authors: midtgaard sr. Proc Natl Acad Sci U S A. 2018 Jun 26;115(26):E6020-E6029. doi: 10.1073/pnas.1806774115. Epub 2018 Jun 13. Proc Natl Acad Sci U S A. 2018. PMID: 29899144 Free PMC article.
Stealth carriers for low-resolution structure determination of membrane proteins in solution.
Maric S, Skar-Gislinge N, Midtgaard S, Thygesen MB, Schiller J, Frielinghaus H, Moulin M, Haertlein M, Forsyth VT, Pomorski TG, Arleth L. Maric S, et al. Acta Crystallogr D Biol Crystallogr. 2014 Feb;70(Pt 2):317-28. doi: 10.1107/S1399004713027466. Epub 2014 Jan 29. Acta Crystallogr D Biol Crystallogr. 2014. PMID: 24531466 Free article.
Aggregative adherence fimbriae form compact structures as seen by SAXS.
Jønsson R, Björling A, Midtgaard SR, Jensen GV, Skar-Gislinge N, Arleth L, Matthews S, Krogfelt KA, Jenssen H. Jønsson R, et al. Among authors: midtgaard sr. Sci Rep. 2023 Oct 2;13(1):16516. doi: 10.1038/s41598-023-42079-0. Sci Rep. 2023. PMID: 37783694 Free PMC article.
Invisible detergents for structure determination of membrane proteins by small-angle neutron scattering.
Midtgaard SR, Darwish TA, Pedersen MC, Huda P, Larsen AH, Jensen GV, Kynde SAR, Skar-Gislinge N, Nielsen AJZ, Olesen C, Blaise M, Dorosz JJ, Thorsen TS, Venskutonytė R, Krintel C, Møller JV, Frielinghaus H, Gilbert EP, Martel A, Kastrup JS, Jensen PE, Nissen P, Arleth L. Midtgaard SR, et al. FEBS J. 2018 Jan;285(2):357-371. doi: 10.1111/febs.14345. Epub 2017 Dec 30. FEBS J. 2018. PMID: 29178440 Free article.
A high-affinity, bivalent PDZ domain inhibitor complexes PICK1 to alleviate neuropathic pain.
Christensen NR, De Luca M, Lever MB, Richner M, Hansen AB, Noes-Holt G, Jensen KL, Rathje M, Jensen DB, Erlendsson S, Bartling CR, Ammendrup-Johnsen I, Pedersen SE, Schönauer M, Nissen KB, Midtgaard SR, Teilum K, Arleth L, Sørensen AT, Bach A, Strømgaard K, Meehan CF, Vaegter CB, Gether U, Madsen KL. Christensen NR, et al. Among authors: midtgaard sr. EMBO Mol Med. 2020 Jun 8;12(6):e11248. doi: 10.15252/emmm.201911248. Epub 2020 Apr 30. EMBO Mol Med. 2020. PMID: 32352640 Free PMC article.
An intermolecular binding mechanism involving multiple LysM domains mediates carbohydrate recognition by an endopeptidase.
Wong JE, Midtgaard SR, Gysel K, Thygesen MB, Sørensen KK, Jensen KJ, Stougaard J, Thirup S, Blaise M. Wong JE, et al. Among authors: midtgaard sr. Acta Crystallogr D Biol Crystallogr. 2015 Mar;71(Pt 3):592-605. doi: 10.1107/S139900471402793X. Epub 2015 Feb 26. Acta Crystallogr D Biol Crystallogr. 2015. PMID: 25760608 Free PMC article.
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