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Age Correlates with Response to Anti-PD1, Reflecting Age-Related Differences in Intratumoral Effector and Regulatory T-Cell Populations.
Kugel CH 3rd, Douglass SM, Webster MR, Kaur A, Liu Q, Yin X, Weiss SA, Darvishian F, Al-Rohil RN, Ndoye A, Behera R, Alicea GM, Ecker BL, Fane M, Allegrezza MJ, Svoronos N, Kumar V, Wang DY, Somasundaram R, Hu-Lieskovan S, Ozgun A, Herlyn M, Conejo-Garcia JR, Gabrilovich D, Stone EL, Nowicki TS, Sosman J, Rai R, Carlino MS, Long GV, Marais R, Ribas A, Eroglu Z, Davies MA, Schilling B, Schadendorf D, Xu W, Amaravadi RK, Menzies AM, McQuade JL, Johnson DB, Osman I, Weeraratna AT. Kugel CH 3rd, et al. Among authors: svoronos n. Clin Cancer Res. 2018 Nov 1;24(21):5347-5356. doi: 10.1158/1078-0432.CCR-18-1116. Epub 2018 Jun 13. Clin Cancer Res. 2018. PMID: 29898988 Free PMC article.
The Tumor Macroenvironment: Cancer-Promoting Networks Beyond Tumor Beds.
Rutkowski MR, Svoronos N, Perales-Puchalt A, Conejo-Garcia JR. Rutkowski MR, et al. Among authors: svoronos n. Adv Cancer Res. 2015;128:235-62. doi: 10.1016/bs.acr.2015.04.011. Epub 2015 May 21. Adv Cancer Res. 2015. PMID: 26216635 Free PMC article. Review.
IL15 Agonists Overcome the Immunosuppressive Effects of MEK Inhibitors.
Allegrezza MJ, Rutkowski MR, Stephen TL, Svoronos N, Tesone AJ, Perales-Puchalt A, Nguyen JM, Sarmin F, Sheen MR, Jeng EK, Tchou J, Wong HC, Fiering SN, Conejo-Garcia JR. Allegrezza MJ, et al. Among authors: svoronos n. Cancer Res. 2016 May 1;76(9):2561-72. doi: 10.1158/0008-5472.CAN-15-2808. Epub 2016 Mar 15. Cancer Res. 2016. PMID: 26980764 Free PMC article.
Follicle-Stimulating Hormone Receptor Is Expressed by Most Ovarian Cancer Subtypes and Is a Safe and Effective Immunotherapeutic Target.
Perales-Puchalt A, Svoronos N, Rutkowski MR, Allegrezza MJ, Tesone AJ, Payne KK, Wickramasinghe J, Nguyen JM, O'Brien SW, Gumireddy K, Huang Q, Cadungog MG, Connolly DC, Tchou J, Curiel TJ, Conejo-Garcia JR. Perales-Puchalt A, et al. Among authors: svoronos n. Clin Cancer Res. 2017 Jan 15;23(2):441-453. doi: 10.1158/1078-0432.CCR-16-0492. Epub 2016 Jul 19. Clin Cancer Res. 2017. PMID: 27435394 Free PMC article.
Estrogens drive myeloid-derived suppressor cell accumulation.
Conejo-Garcia JR, Payne KK, Svoronos N. Conejo-Garcia JR, et al. Among authors: svoronos n. Oncoscience. 2017 Feb 24;4(1-2):5-6. doi: 10.18632/oncoscience.340. eCollection 2017 Jan. Oncoscience. 2017. PMID: 28484727 Free PMC article. No abstract available.
Tumor Cell-Independent Estrogen Signaling Drives Disease Progression through Mobilization of Myeloid-Derived Suppressor Cells.
Svoronos N, Perales-Puchalt A, Allegrezza MJ, Rutkowski MR, Payne KK, Tesone AJ, Nguyen JM, Curiel TJ, Cadungog MG, Singhal S, Eruslanov EB, Zhang P, Tchou J, Zhang R, Conejo-Garcia JR. Svoronos N, et al. Cancer Discov. 2017 Jan;7(1):72-85. doi: 10.1158/2159-8290.CD-16-0502. Epub 2016 Sep 30. Cancer Discov. 2017. PMID: 27694385 Free PMC article.
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