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A two-site flexible clamp mechanism for RET-GDNF-GFRα1 assembly reveals both conformational adaptation and strict geometric spacing.
Adams SE, Purkiss AG, Knowles PP, Nans A, Briggs DC, Borg A, Earl CP, Goodman KM, Nawrotek A, Borg AJ, McIntosh PB, Houghton FM, Kjær S, McDonald NQ. Adams SE, et al. Among authors: borg aj, borg a. Structure. 2021 Jul 1;29(7):694-708.e7. doi: 10.1016/j.str.2020.12.012. Epub 2021 Jan 22. Structure. 2021. PMID: 33484636 Free PMC article.
Neutralising antibodies after COVID-19 vaccination in UK haemodialysis patients.
Carr EJ, Wu M, Harvey R, Wall EC, Kelly G, Hussain S, Howell M, Kassiotis G, Swanton C, Gandhi S, Bauer DL; Haemodialysis COVID-19 consortium; Crick COVID Immunity Pipeline; Billany RE, Graham-Brown MP, Beckett J, Bull K, Shankar S, Henderson S, Motallebzadeh R, Salama AD, Harper L, Mark PB, McAdoo S, Willicombe M, Beale R. Carr EJ, et al. Lancet. 2021 Sep 18;398(10305):1038-1041. doi: 10.1016/S0140-6736(21)01854-7. Epub 2021 Aug 13. Lancet. 2021. PMID: 34391504 Free PMC article. No abstract available.
O-Linked Sialoglycans Modulate the Proteolysis of SARS-CoV-2 Spike and Likely Contribute to the Mutational Trajectory in Variants of Concern.
Gonzalez-Rodriguez E, Zol-Hanlon M, Bineva-Todd G, Marchesi A, Skehel M, Mahoney KE, Roustan C, Borg A, Di Vagno L, Kjær S, Wrobel AG, Benton DJ, Nawrath P, Flitsch SL, Joshi D, González-Ramírez AM, Wilkinson KA, Wilkinson RJ, Wall EC, Hurtado-Guerrero R, Malaker SA, Schumann B. Gonzalez-Rodriguez E, et al. Among authors: borg a. ACS Cent Sci. 2023 Feb 16;9(3):393-404. doi: 10.1021/acscentsci.2c01349. eCollection 2023 Mar 22. ACS Cent Sci. 2023. PMID: 36968546 Free PMC article.
Strong peak immunogenicity but rapid antibody waning following third vaccine dose in older residents of care homes.
Tut G, Lancaster T, Krutikov M, Sylla P, Bone D, Spalkova E, Bentley C, Amin U, Jadir A, Hulme S, Kaur N, Tut E, Bruton R, Wu MY, Harvey R, Carr EJ; Crick COVID Immunity Pipeline; Beale R, Stirrup O, Shrotri M, Azmi B, Fuller C, Baynton V, Irwin-Singer A, Hayward A, Copas A, Shallcross L, Moss P. Tut G, et al. Nat Aging. 2023 Jan;3(1):93-104. doi: 10.1038/s43587-022-00328-3. Epub 2023 Jan 20. Nat Aging. 2023. PMID: 37118525 Free PMC article.
842 results