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Page 1
Autophagy in cancer: a complex relationship.
Wilde L, Tanson K, Curry J, Martinez-Outschoorn U. Wilde L, et al. Biochem J. 2018 Jun 11;475(11):1939-1954. doi: 10.1042/BCJ20170847. Biochem J. 2018. PMID: 29891531 Review.
Tumor cells induce the cancer associated fibroblast phenotype via caveolin-1 degradation: implications for breast cancer and DCIS therapy with autophagy inhibitors.
Martinez-Outschoorn UE, Pavlides S, Whitaker-Menezes D, Daumer KM, Milliman JN, Chiavarina B, Migneco G, Witkiewicz AK, Martinez-Cantarin MP, Flomenberg N, Howell A, Pestell RG, Lisanti MP, Sotgia F. Martinez-Outschoorn UE, et al. Cell Cycle. 2010 Jun 15;9(12):2423-33. doi: 10.4161/cc.9.12.12048. Epub 2010 Jun 15. Cell Cycle. 2010. PMID: 20562526
Autophagy in cancer associated fibroblasts promotes tumor cell survival: Role of hypoxia, HIF1 induction and NFκB activation in the tumor stromal microenvironment.
Martinez-Outschoorn UE, Trimmer C, Lin Z, Whitaker-Menezes D, Chiavarina B, Zhou J, Wang C, Pavlides S, Martinez-Cantarin MP, Capozza F, Witkiewicz AK, Flomenberg N, Howell A, Pestell RG, Caro J, Lisanti MP, Sotgia F. Martinez-Outschoorn UE, et al. Cell Cycle. 2010 Sep 1;9(17):3515-33. doi: 10.4161/cc.9.17.12928. Epub 2010 Sep 9. Cell Cycle. 2010. PMID: 20855962 Free PMC article.
Understanding the "lethal" drivers of tumor-stroma co-evolution: emerging role(s) for hypoxia, oxidative stress and autophagy/mitophagy in the tumor micro-environment.
Lisanti MP, Martinez-Outschoorn UE, Chiavarina B, Pavlides S, Whitaker-Menezes D, Tsirigos A, Witkiewicz A, Lin Z, Balliet R, Howell A, Sotgia F. Lisanti MP, et al. Cancer Biol Ther. 2010 Sep 15;10(6):537-42. doi: 10.4161/cbt.10.6.13370. Epub 2010 Sep 19. Cancer Biol Ther. 2010. PMID: 20861671 Free PMC article. Review.
HIF1-alpha functions as a tumor promoter in cancer associated fibroblasts, and as a tumor suppressor in breast cancer cells: Autophagy drives compartment-specific oncogenesis.
Chiavarina B, Whitaker-Menezes D, Migneco G, Martinez-Outschoorn UE, Pavlides S, Howell A, Tanowitz HB, Casimiro MC, Wang C, Pestell RG, Grieshaber P, Caro J, Sotgia F, Lisanti MP. Chiavarina B, et al. Cell Cycle. 2010 Sep 1;9(17):3534-51. doi: 10.4161/cc.9.17.12908. Epub 2010 Sep 4. Cell Cycle. 2010. PMID: 20864819 Free PMC article.
The autophagic tumor stroma model of cancer or "battery-operated tumor growth": A simple solution to the autophagy paradox.
Martinez-Outschoorn UE, Whitaker-Menezes D, Pavlides S, Chiavarina B, Bonuccelli G, Casey T, Tsirigos A, Migneco G, Witkiewicz A, Balliet R, Mercier I, Wang C, Flomenberg N, Howell A, Lin Z, Caro J, Pestell RG, Sotgia F, Lisanti MP. Martinez-Outschoorn UE, et al. Cell Cycle. 2010 Nov 1;9(21):4297-306. doi: 10.4161/cc.9.21.13817. Epub 2010 Nov 30. Cell Cycle. 2010. PMID: 21051947 Free PMC article. Review.
Warburg meets autophagy: cancer-associated fibroblasts accelerate tumor growth and metastasis via oxidative stress, mitophagy, and aerobic glycolysis.
Pavlides S, Vera I, Gandara R, Sneddon S, Pestell RG, Mercier I, Martinez-Outschoorn UE, Whitaker-Menezes D, Howell A, Sotgia F, Lisanti MP. Pavlides S, et al. Antioxid Redox Signal. 2012 Jun 1;16(11):1264-84. doi: 10.1089/ars.2011.4243. Epub 2011 Nov 17. Antioxid Redox Signal. 2012. PMID: 21883043 Free PMC article. Review.
138 results