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An engineered cell line lacking OGG1 and MUTYH glycosylases implicates the accumulation of genomic 8-oxoguanine as the basis for paraquat mutagenicity.
Tajai P, Fedeles BI, Suriyo T, Navasumrit P, Kanitwithayanun J, Essigmann JM, Satayavivad J. Tajai P, et al. Among authors: kanitwithayanun j. Free Radic Biol Med. 2018 Feb 20;116:64-72. doi: 10.1016/j.freeradbiomed.2017.12.035. Epub 2017 Dec 28. Free Radic Biol Med. 2018. PMID: 29289706 Free PMC article.