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Hexokinase 2 is targetable for HK1 negative, HK2 positive tumors from a wide variety of tissues of origin.
J Nucl Med. 2018 Jun 7;60(2):212-7. doi: 10.2967/jnumed.118.212365. Online ahead of print.
J Nucl Med. 2018.
PMID: 29880505
Free PMC article.
An HK2 Antisense Oligonucleotide Induces Synthetic Lethality in HK1-HK2+ Multiple Myeloma.
Xu S, Zhou T, Doh HM, Trinh KR, Catapang A, Lee JT, Braas D, Bayley NA, Yamada RE, Vasuthasawat A, Sasine JP, Timmerman JM, Larson SM, Kim Y, MacLeod AR, Morrison SL, Herschman HR.
Xu S, et al. Among authors: catapang a.
Cancer Res. 2019 May 15;79(10):2748-2760. doi: 10.1158/0008-5472.CAN-18-2799. Epub 2019 Mar 18.
Cancer Res. 2019.
PMID: 30885978
Free PMC article.
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A precision therapeutic strategy for hexokinase 1-null, hexokinase 2-positive cancers.
Xu S, Catapang A, Braas D, Stiles L, Doh HM, Lee JT, Graeber TG, Damoiseaux R, Shirihai O, Herschman HR.
Xu S, et al. Among authors: catapang a.
Cancer Metab. 2018 Jun 28;6:7. doi: 10.1186/s40170-018-0181-8. eCollection 2018.
Cancer Metab. 2018.
PMID: 29988332
Free PMC article.
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Targeted Cox2 gene deletion in intestinal epithelial cells decreases tumorigenesis in female, but not male, ApcMin/+ mice.
Cherukuri DP, Ishikawa TO, Chun P, Catapang A, Elashoff D, Grogan TR, Bugni J, Herschman HR.
Cherukuri DP, et al. Among authors: catapang a.
Mol Oncol. 2014 Mar;8(2):169-77. doi: 10.1016/j.molonc.2013.10.009. Epub 2013 Nov 8.
Mol Oncol. 2014.
PMID: 24268915
Free PMC article.
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Targeted deletion and lipidomic analysis identify epithelial cell COX-2 as a major driver of chemically induced skin cancer.
Jiao J, Ishikawa TO, Dumlao DS, Norris PC, Magyar CE, Mikulec C, Catapang A, Dennis EA, Fischer SM, Herschman HR.
Jiao J, et al. Among authors: catapang a.
Mol Cancer Res. 2014 Nov;12(11):1677-88. doi: 10.1158/1541-7786.MCR-14-0397-T. Epub 2014 Jul 25.
Mol Cancer Res. 2014.
PMID: 25063587
Free PMC article.
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Reversible suppression of cyclooxygenase 2 (COX-2) expression in vivo by inducible RNA interference.
Zaiss AK, Zuber J, Chu C, Machado HB, Jiao J, Catapang AB, Ishikawa TO, Gil JS, Lowe SW, Herschman HR.
Zaiss AK, et al. Among authors: catapang ab.
PLoS One. 2014 Jul 2;9(7):e101263. doi: 10.1371/journal.pone.0101263. eCollection 2014.
PLoS One. 2014.
PMID: 24988319
Free PMC article.
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Hepatocyte Heparan Sulfate Is Required for Adeno-Associated Virus 2 but Dispensable for Adenovirus 5 Liver Transduction In Vivo.
Zaiss AK, Foley EM, Lawrence R, Schneider LS, Hoveida H, Secrest P, Catapang AB, Yamaguchi Y, Alemany R, Shayakhmetov DM, Esko JD, Herschman HR.
Zaiss AK, et al. Among authors: catapang ab.
J Virol. 2015 Oct 21;90(1):412-20. doi: 10.1128/JVI.01939-15. Print 2016 Jan 1.
J Virol. 2015.
PMID: 26491162
Free PMC article.
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