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The Rho regulator Myosin IXb enables nonlymphoid tissue seeding of protective CD8+ T cells.
Moalli F, Ficht X, Germann P, Vladymyrov M, Stolp B, de Vries I, Lyck R, Balmer J, Fiocchi A, Kreutzfeldt M, Merkler D, Iannacone M, Ariga A, Stoffel MH, Sharpe J, Bähler M, Sixt M, Diz-Muñoz A, Stein JV. Moalli F, et al. Among authors: bahler m. J Exp Med. 2018 Jul 2;215(7):1869-1890. doi: 10.1084/jem.20170896. Epub 2018 Jun 6. J Exp Med. 2018. PMID: 29875261 Free PMC article.
Class IX Myosins: Motorized RhoGAP Signaling Molecules.
Hanley PJ, Vollmer V, Bähler M. Hanley PJ, et al. Among authors: bahler m. Adv Exp Med Biol. 2020;1239:381-389. doi: 10.1007/978-3-030-38062-5_16. Adv Exp Med Biol. 2020. PMID: 32451867 Review.
Motorized RhoGAP myosin IXb (Myo9b) controls cell shape and motility.
Hanley PJ, Xu Y, Kronlage M, Grobe K, Schön P, Song J, Sorokin L, Schwab A, Bähler M. Hanley PJ, et al. Among authors: bahler m. Proc Natl Acad Sci U S A. 2010 Jul 6;107(27):12145-50. doi: 10.1073/pnas.0911986107. Epub 2010 Jun 21. Proc Natl Acad Sci U S A. 2010. PMID: 20566876 Free PMC article.
Rho GAP myosin IXa is a regulator of kidney tubule function.
Thelen S, Abouhamed M, Ciarimboli G, Edemir B, Bähler M. Thelen S, et al. Among authors: bahler m. Am J Physiol Renal Physiol. 2015 Sep 15;309(6):F501-13. doi: 10.1152/ajprenal.00220.2014. Epub 2015 Jul 1. Am J Physiol Renal Physiol. 2015. PMID: 26136556 Free article.
Local Myo9b RhoGAP activity regulates cell motility.
Hemkemeyer SA, Vollmer V, Schwarz V, Lohmann B, Honnert U, Taha M, Schnittler HJ, Bähler M. Hemkemeyer SA, et al. Among authors: bahler m. J Biol Chem. 2021 Jan-Jun;296:100136. doi: 10.1074/jbc.RA120.013623. Epub 2020 Dec 6. J Biol Chem. 2021. PMID: 33268376 Free PMC article.
Mouse macrophages completely lacking Rho subfamily GTPases (RhoA, RhoB, and RhoC) have severe lamellipodial retraction defects, but robust chemotactic navigation and altered motility.
Königs V, Jennings R, Vogl T, Horsthemke M, Bachg AC, Xu Y, Grobe K, Brakebusch C, Schwab A, Bähler M, Knaus UG, Hanley PJ. Königs V, et al. Among authors: bahler m. J Biol Chem. 2014 Oct 31;289(44):30772-30784. doi: 10.1074/jbc.M114.563270. Epub 2014 Sep 11. J Biol Chem. 2014. PMID: 25213860 Free PMC article.
101 results