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Renal immune surveillance and dipeptidase-1 contribute to contrast-induced acute kidney injury.
Lau A, Chung H, Komada T, Platnich JM, Sandall CF, Choudhury SR, Chun J, Naumenko V, Surewaard BG, Nelson MC, Ulke-Lemée A, Beck PL, Benediktsson H, Jevnikar AM, Snelgrove SL, Hickey MJ, Senger DL, James MT, Macdonald JA, Kubes P, Jenne CN, Muruve DA. Lau A, et al. Among authors: komada t. J Clin Invest. 2018 Jul 2;128(7):2894-2913. doi: 10.1172/JCI96640. Epub 2018 Jun 4. J Clin Invest. 2018. PMID: 29863495 Free PMC article.
Shiga Toxin/Lipopolysaccharide Activates Caspase-4 and Gasdermin D to Trigger Mitochondrial Reactive Oxygen Species Upstream of the NLRP3 Inflammasome.
Platnich JM, Chung H, Lau A, Sandall CF, Bondzi-Simpson A, Chen HM, Komada T, Trotman-Grant AC, Brandelli JR, Chun J, Beck PL, Philpott DJ, Girardin SE, Ho M, Johnson RP, MacDonald JA, Armstrong GD, Muruve DA. Platnich JM, et al. Among authors: komada t. Cell Rep. 2018 Nov 6;25(6):1525-1536.e7. doi: 10.1016/j.celrep.2018.09.071. Cell Rep. 2018. PMID: 30404007 Free article.
The role of inflammasomes in kidney disease.
Komada T, Muruve DA. Komada T, et al. Nat Rev Nephrol. 2019 Aug;15(8):501-520. doi: 10.1038/s41581-019-0158-z. Nat Rev Nephrol. 2019. PMID: 31164720 Review.
NLRP3 Inflammasome Activation in Lung Vascular Endothelial Cells Contributes to Intestinal Ischemia/Reperfusion-Induced Acute Lung Injury.
Ito H, Kimura H, Karasawa T, Hisata S, Sadatomo A, Inoue Y, Yamada N, Aizawa E, Hishida E, Kamata R, Komada T, Watanabe S, Kasahara T, Suzuki T, Horie H, Kitayama J, Sata N, Yamaji-Kegan K, Takahashi M. Ito H, et al. Among authors: komada t. J Immunol. 2020 Sep 1;205(5):1393-1405. doi: 10.4049/jimmunol.2000217. Epub 2020 Jul 29. J Immunol. 2020. PMID: 32727891
NLRP3 protein deficiency exacerbates hyperoxia-induced lethality through Stat3 protein signaling independent of interleukin-1β.
Mizushina Y, Shirasuna K, Usui F, Karasawa T, Kawashima A, Kimura H, Kobayashi M, Komada T, Inoue Y, Mato N, Yamasawa H, Latz E, Iwakura Y, Kasahara T, Bando M, Sugiyama Y, Takahashi M. Mizushina Y, et al. Among authors: komada t. J Biol Chem. 2015 Feb 20;290(8):5065-5077. doi: 10.1074/jbc.M114.603217. Epub 2014 Dec 29. J Biol Chem. 2015. PMID: 25548278 Free PMC article.
117 results