Braun F - Search Results

1

Structure-based design and profiling of novel 17β-HSD14 inhibitors.

Braun F, Bertoletti N, Möller G, Adamski J, Frotscher M, Guragossian N, Madeira Gírio PA, Le Borgne M, Ettouati L, Falson P, Müller S, Vollmer G, Heine A, Klebe G, Marchais-Oberwinkler S. Braun F, et al. Eur J Med Chem. 2018 Jul 15;155:61-76. doi: 10.1016/j.ejmech.2018.05.029. Epub 2018 May 22. Eur J Med Chem. 2018. PMID: 29859505

2

New Insights into Human 17β-Hydroxysteroid Dehydrogenase Type 14: First Crystal Structures in Complex with a Steroidal Ligand and with a Potent Nonsteroidal Inhibitor.

Bertoletti N, Braun F, Lepage M, Möller G, Adamski J, Heine A, Klebe G, Marchais-Oberwinkler S. Bertoletti N, et al. Among authors: braun f. J Med Chem. 2016 Jul 28;59(14):6961-7. doi: 10.1021/acs.jmedchem.6b00293. Epub 2016 Jul 12. J Med Chem. 2016. PMID: 27362750

3

First Structure-Activity Relationship of 17β-Hydroxysteroid Dehydrogenase Type 14 Nonsteroidal Inhibitors and Crystal Structures in Complex with the Enzyme.

Braun F, Bertoletti N, Möller G, Adamski J, Steinmetzer T, Salah M, Abdelsamie AS, van Koppen CJ, Heine A, Klebe G, Marchais-Oberwinkler S. Braun F, et al. J Med Chem. 2016 Dec 8;59(23):10719-10737. doi: 10.1021/acs.jmedchem.6b01436. Epub 2016 Nov 18. J Med Chem. 2016. PMID: 27933965

4

Semisynthetic cephalosporins. Synthesis and structure-activity relationships of 7-(1-pyrryl)- and 7-(1-indolyl)acetamidocephalosporin derivatives.

Nudelman A, Karoly H, Braun F, Böhme EH, Erickson RC. Nudelman A, et al. Among authors: braun f. J Med Chem. 1978 Sep;21(9):962-4. doi: 10.1021/jm00207a022. J Med Chem. 1978. PMID: 722761

5

Semisynthetic cephalosporins. III. Synthesis and structure activity relationships of novel orally active 7-[4-hydroxy-3-(substituted methyl)phenyl]-acetamido-3-cephem-4-carboxylic acids.

Nudelman A, Patchornick A, Karoly-Hafely E, Braun F, Erickson RC. Nudelman A, et al. Among authors: braun f. J Antibiot (Tokyo). 1980 Jan;33(1):76-82. doi: 10.7164/antibiotics.33.76. J Antibiot (Tokyo). 1980. PMID: 7372553 Free article.

6

Three-dimensional solubility parameters and their use in characterising the permeation of drugs through the skin.

Groning R, Braun FJ. Groning R, et al. Among authors: braun fj. Pharmazie. 1996 May;51(5):337-41. Pharmazie. 1996. PMID: 8710956

7

CD57 defines a novel cancer stem cell that drive invasion of diffuse pediatric-type high grade gliomas.

Qi L, Du Y, Huang Y, Kogiso M, Zhang H, Xiao S, Abdallah A, Suarez M, Niu L, Liu ZG, Lindsay H, Braun FK, Stephen C, Davies PJ, Teo WY, Adenkunle A, Baxter P, Su JM, Li XN. Qi L, et al. Among authors: braun fk. Br J Cancer. 2024 Jun 4. doi: 10.1038/s41416-024-02724-5. Online ahead of print. Br J Cancer. 2024. PMID: 38834745

8

Engineering Dimeric EGFR-directed IgA Antibodies Reveals a Central Role of CD147 during Neutrophil-mediated Tumor Cell Killing of Head and Neck Squamous Cancer Cells.

Zwick A, Braun FL, Weber LJ, Linder M, Linxweiler M, Lohse S. Zwick A, et al. Among authors: braun fl. J Immunol. 2024 May 24:ji2300544. doi: 10.4049/jimmunol.2300544. Online ahead of print. J Immunol. 2024. PMID: 38787053

9

Direct Implantation of Patient Brain Tumor Cells into Matching Locations in Mouse Brains for Patient-Derived Orthotopic Xenograft Model Development.

Qi L, Baxter P, Kogiso M, Zhang H, Braun FK, Lindsay H, Zhao S, Xiao S, Abdallah AS, Suarez M, Huang Z, Teo WY, Yu L, Zhao X, Liu Z, Huang Y, Su JM, Man TK, Lau CC, Perlaky L, Du Y, Li XN. Qi L, et al. Among authors: braun fk. Cancers (Basel). 2024 Apr 28;16(9):1716. doi: 10.3390/cancers16091716. Cancers (Basel). 2024. PMID: 38730671 Free PMC article.

10

Extracellular vesicles secreted by 3D tumor organoids are enriched for immune regulatory signaling biomolecules compared to conventional 2D glioblastoma cell systems.

Schuster M, Braun FK, Chiang DM, Ludwig C, Meng C, Grätz C, Kirchner B, Proescholdt M, Hau P, Steinlein OK, Pfaffl MW, Riemenschneider MJ, Reithmair M. Schuster M, et al. Among authors: braun fk. Front Immunol. 2024 Apr 25;15:1388769. doi: 10.3389/fimmu.2024.1388769. eCollection 2024. Front Immunol. 2024. PMID: 38726003 Free PMC article.

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