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Reduction of N-hydroxy-sulfonamides, including N-hydroxy-valdecoxib, by the molybdenum-containing enzyme mARC.
Havemeyer A, Grünewald S, Wahl B, Bittner F, Mendel R, Erdélyi P, Fischer J, Clement B. Havemeyer A, et al. Drug Metab Dispos. 2010 Nov;38(11):1917-21. doi: 10.1124/dmd.110.032813. Epub 2010 Aug 10. Drug Metab Dispos. 2010. PMID: 20699408
Purification of the mitochondrial enzyme responsible for reduction of N-hydroxylated amidine prodrugs led to the identification of two newly discovered mammalian molybdenum-containing proteins, the mitochondrial amidoxime reducing components mARC-1 and mARC-2 (Gruenewald et al., …
Purification of the mitochondrial enzyme responsible for reduction of N-hydroxylated amidine prodrugs led to the identification of two newly …
The mammalian molybdenum enzymes of mARC.
Ott G, Havemeyer A, Clement B. Ott G, et al. Among authors: havemeyer a. J Biol Inorg Chem. 2015 Mar;20(2):265-75. doi: 10.1007/s00775-014-1216-4. Epub 2014 Nov 26. J Biol Inorg Chem. 2015. PMID: 25425164 Review.
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