Simon E - Search Results

1

Discovery and translation of a target engagement marker for AMP-activated protein kinase (AMPK).

Grempler R, Wolff M, Simon E, Schmid R, Eisele C, Rieber K, Fischer E, Mettel S, Gabrielyan O, Delic D, Luippold G, Redeman N. Grempler R, et al. Among authors: simon e. PLoS One. 2018 May 25;13(5):e0197849. doi: 10.1371/journal.pone.0197849. eCollection 2018. PLoS One. 2018. PMID: 29799853 Free PMC article.

2

Functional characterisation of human SGLT-5 as a novel kidney-specific sodium-dependent sugar transporter.

Grempler R, Augustin R, Froehner S, Hildebrandt T, Simon E, Mark M, Eickelmann P. Grempler R, et al. Among authors: simon e. FEBS Lett. 2012 Feb 3;586(3):248-53. doi: 10.1016/j.febslet.2011.12.027. Epub 2011 Dec 30. FEBS Lett. 2012. PMID: 22212718 Free article.

3

Biomarker discovery for chronic liver diseases by multi-omics - a preclinical case study.

Veyel D, Wenger K, Broermann A, Bretschneider T, Luippold AH, Krawczyk B, Rist W, Simon E. Veyel D, et al. Among authors: simon e. Sci Rep. 2020 Jan 28;10(1):1314. doi: 10.1038/s41598-020-58030-6. Sci Rep. 2020. PMID: 31992752 Free PMC article.

4

Deletion of the diabetes candidate gene Slc16a13 in mice attenuates diet-induced ectopic lipid accumulation and insulin resistance.

Schumann T, König J, von Loeffelholz C, Vatner DF, Zhang D, Perry RJ, Bernier M, Chami J, Henke C, Kurzbach A, El-Agroudy NN, Willmes DM, Pesta D, de Cabo R, O Sullivan JF, Simon E, Shulman GI, Hamilton BS, Birkenfeld AL. Schumann T, et al. Among authors: simon e. Commun Biol. 2021 Jul 1;4(1):826. doi: 10.1038/s42003-021-02279-8. Commun Biol. 2021. PMID: 34211098 Free PMC article.

5

Upscaling of hiPS Cell-Derived Neurons for High-Throughput Screening.

Traub S, Stahl H, Rosenbrock H, Simon E, Heilker R. Traub S, et al. Among authors: simon e. SLAS Discov. 2017 Mar;22(3):274-286. doi: 10.1177/1087057116678161. Epub 2016 Nov 16. SLAS Discov. 2017. PMID: 28231034 Free article.

6

Pharmaceutical Characterization of Tropomyosin Receptor Kinase B-Agonistic Antibodies on Human Induced Pluripotent Stem (hiPS) Cell-Derived Neurons.

Traub S, Stahl H, Rosenbrock H, Simon E, Florin L, Hospach L, Hörer S, Heilker R. Traub S, et al. Among authors: simon e. J Pharmacol Exp Ther. 2017 Jun;361(3):355-365. doi: 10.1124/jpet.117.240184. Epub 2017 Mar 28. J Pharmacol Exp Ther. 2017. PMID: 28351853

7

An RNA-Seq atlas of gene expression in mouse and rat normal tissues.

Söllner JF, Leparc G, Hildebrandt T, Klein H, Thomas L, Stupka E, Simon E. Söllner JF, et al. Among authors: simon e. Sci Data. 2017 Dec 12;4:170185. doi: 10.1038/sdata.2017.185. Sci Data. 2017. PMID: 29231921 Free PMC article.

8

Exploiting orthology and de novo transcriptome assembly to refine target sequence information.

Söllner JF, Leparc G, Zwick M, Schönberger T, Hildebrandt T, Nieselt K, Simon E. Söllner JF, et al. Among authors: simon e. BMC Med Genomics. 2019 May 23;12(1):69. doi: 10.1186/s12920-019-0524-5. BMC Med Genomics. 2019. PMID: 31122257 Free PMC article.

9

In-depth transcriptomic analysis of human retina reveals molecular mechanisms underlying diabetic retinopathy.

Becker K, Klein H, Simon E, Viollet C, Haslinger C, Leparc G, Schultheis C, Chong V, Kuehn MH, Fernandez-Albert F, Bakker RA. Becker K, et al. Among authors: simon e. Sci Rep. 2021 May 18;11(1):10494. doi: 10.1038/s41598-021-88698-3. Sci Rep. 2021. PMID: 34006945 Free PMC article.

10

BI 456906: Discovery and preclinical pharmacology of a novel GCGR/GLP-1R dual agonist with robust anti-obesity efficacy.

Zimmermann T, Thomas L, Baader-Pagler T, Haebel P, Simon E, Reindl W, Bajrami B, Rist W, Uphues I, Drucker DJ, Klein H, Santhanam R, Hamprecht D, Neubauer H, Augustin R. Zimmermann T, et al. Among authors: simon e. Mol Metab. 2022 Dec;66:101633. doi: 10.1016/j.molmet.2022.101633. Epub 2022 Nov 7. Mol Metab. 2022. PMID: 36356832 Free PMC article.

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