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Generation of synthetic nanobodies against delicate proteins.
Zimmermann I, Egloff P, Hutter CAJ, Kuhn BT, Bräuer P, Newstead S, Dawson RJP, Geertsma ER, Seeger MA. Zimmermann I, et al. Nat Protoc. 2020 May;15(5):1707-1741. doi: 10.1038/s41596-020-0304-x. Epub 2020 Apr 8. Nat Protoc. 2020. PMID: 32269381
Biotinylation of Membrane Proteins for Binder Selections.
Kuhn BT, Zimmermann I, Egloff P, Hürlimann LM, Hutter CAJ, Miscenic C, Dawson RJP, Seeger MA, Geertsma ER. Kuhn BT, et al. Among authors: zimmermann i. Methods Mol Biol. 2020;2127:151-165. doi: 10.1007/978-1-0716-0373-4_11. Methods Mol Biol. 2020. PMID: 32112321 Free article.
The extracellular gate shapes the energy profile of an ABC exporter.
Hutter CAJ, Timachi MH, Hürlimann LM, Zimmermann I, Egloff P, Göddeke H, Kucher S, Štefanić S, Karttunen M, Schäfer LV, Bordignon E, Seeger MA. Hutter CAJ, et al. Among authors: zimmermann i. Nat Commun. 2019 May 21;10(1):2260. doi: 10.1038/s41467-019-09892-6. Nat Commun. 2019. PMID: 31113958 Free PMC article.
The ABC exporter IrtAB imports and reduces mycobacterial siderophores.
Arnold FM, Weber MS, Gonda I, Gallenito MJ, Adenau S, Egloff P, Zimmermann I, Hutter CAJ, Hürlimann LM, Peters EE, Piel J, Meloni G, Medalia O, Seeger MA. Arnold FM, et al. Among authors: zimmermann i. Nature. 2020 Apr;580(7803):413-417. doi: 10.1038/s41586-020-2136-9. Epub 2020 Mar 25. Nature. 2020. PMID: 32296173 Free PMC article.
Structural insights into the inhibition of glycine reuptake.
Shahsavar A, Stohler P, Bourenkov G, Zimmermann I, Siegrist M, Guba W, Pinard E, Sinning S, Seeger MA, Schneider TR, Dawson RJP, Nissen P. Shahsavar A, et al. Among authors: zimmermann i. Nature. 2021 Mar;591(7851):677-681. doi: 10.1038/s41586-021-03274-z. Epub 2021 Mar 3. Nature. 2021. PMID: 33658720
Engineered peptide barcodes for in-depth analyses of binding protein libraries.
Egloff P, Zimmermann I, Arnold FM, Hutter CAJ, Morger D, Opitz L, Poveda L, Keserue HA, Panse C, Roschitzki B, Seeger MA. Egloff P, et al. Among authors: zimmermann i. Nat Methods. 2019 May;16(5):421-428. doi: 10.1038/s41592-019-0389-8. Epub 2019 Apr 22. Nat Methods. 2019. PMID: 31011184 Free PMC article.
Biparatopic sybodies neutralize SARS-CoV-2 variants of concern and mitigate drug resistance.
Walter JD, Scherer M, Hutter CAJ, Garaeva AA, Zimmermann I, Wyss M, Rheinberger J, Ruedin Y, Earp JC, Egloff P, Sorgenfrei M, Hürlimann LM, Gonda I, Meier G, Remm S, Thavarasah S, van Geest G, Bruggmann R, Zimmer G, Slotboom DJ, Paulino C, Plattet P, Seeger MA. Walter JD, et al. Among authors: zimmermann i. EMBO Rep. 2022 Apr 5;23(4):e54199. doi: 10.15252/embr.202154199. Epub 2022 Mar 7. EMBO Rep. 2022. PMID: 35253970 Free PMC article.
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