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A20 critically controls microglia activation and inhibits inflammasome-dependent neuroinflammation.
Voet S, Mc Guire C, Hagemeyer N, Martens A, Schroeder A, Wieghofer P, Daems C, Staszewski O, Vande Walle L, Jordao MJC, Sze M, Vikkula HK, Demeestere D, Van Imschoot G, Scott CL, Hoste E, Gonçalves A, Guilliams M, Lippens S, Libert C, Vandenbroucke RE, Kim KW, Jung S, Callaerts-Vegh Z, Callaerts P, de Wit J, Lamkanfi M, Prinz M, van Loo G. Voet S, et al. Among authors: vande walle l. Nat Commun. 2018 May 23;9(1):2036. doi: 10.1038/s41467-018-04376-5. Nat Commun. 2018. PMID: 29789522 Free PMC article.
Toxic proteins released from mitochondria in cell death.
Saelens X, Festjens N, Vande Walle L, van Gurp M, van Loo G, Vandenabeele P. Saelens X, et al. Among authors: vande walle l. Oncogene. 2004 Apr 12;23(16):2861-74. doi: 10.1038/sj.onc.1207523. Oncogene. 2004. PMID: 15077149 Review.
A novel caspase-2 complex containing TRAF2 and RIP1.
Lamkanfi M, D'hondt K, Vande Walle L, van Gurp M, Denecker G, Demeulemeester J, Kalai M, Declercq W, Saelens X, Vandenabeele P. Lamkanfi M, et al. Among authors: vande walle l. J Biol Chem. 2005 Feb 25;280(8):6923-32. doi: 10.1074/jbc.M411180200. Epub 2004 Dec 8. J Biol Chem. 2005. PMID: 15590671 Free article.
Proteome-wide Identification of HtrA2/Omi Substrates.
Vande Walle L, Van Damme P, Lamkanfi M, Saelens X, Vandekerckhove J, Gevaert K, Vandenabeele P. Vande Walle L, et al. J Proteome Res. 2007 Mar;6(3):1006-15. doi: 10.1021/pr060510d. Epub 2007 Feb 1. J Proteome Res. 2007. PMID: 17266347
The mitochondrial serine protease HtrA2/Omi: an overview.
Vande Walle L, Lamkanfi M, Vandenabeele P. Vande Walle L, et al. Cell Death Differ. 2008 Mar;15(3):453-60. doi: 10.1038/sj.cdd.4402291. Epub 2008 Jan 4. Cell Death Differ. 2008. PMID: 18174901 Review.
Inflammasome-dependent release of the alarmin HMGB1 in endotoxemia.
Lamkanfi M, Sarkar A, Vande Walle L, Vitari AC, Amer AO, Wewers MD, Tracey KJ, Kanneganti TD, Dixit VM. Lamkanfi M, et al. Among authors: vande walle l. J Immunol. 2010 Oct 1;185(7):4385-92. doi: 10.4049/jimmunol.1000803. Epub 2010 Aug 27. J Immunol. 2010. PMID: 20802146 Free PMC article.
HMGB1 release by inflammasomes.
Vande Walle L, Kanneganti TD, Lamkanfi M. Vande Walle L, et al. Virulence. 2011 Mar-Apr;2(2):162-5. doi: 10.4161/viru.2.2.15480. Epub 2011 Mar 1. Virulence. 2011. PMID: 21422809 Free PMC article. Review.
Deregulated inflammasome signaling in disease.
Lamkanfi M, Vande Walle L, Kanneganti TD. Lamkanfi M, et al. Among authors: vande walle l. Immunol Rev. 2011 Sep;243(1):163-73. doi: 10.1111/j.1600-065X.2011.01042.x. Immunol Rev. 2011. PMID: 21884175 Free PMC article. Review.
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