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A20 critically controls microglia activation and inhibits inflammasome-dependent neuroinflammation.
Voet S, Mc Guire C, Hagemeyer N, Martens A, Schroeder A, Wieghofer P, Daems C, Staszewski O, Vande Walle L, Jordao MJC, Sze M, Vikkula HK, Demeestere D, Van Imschoot G, Scott CL, Hoste E, Gonçalves A, Guilliams M, Lippens S, Libert C, Vandenbroucke RE, Kim KW, Jung S, Callaerts-Vegh Z, Callaerts P, de Wit J, Lamkanfi M, Prinz M, van Loo G. Voet S, et al. Among authors: hoste e. Nat Commun. 2018 May 23;9(1):2036. doi: 10.1038/s41467-018-04376-5. Nat Commun. 2018. PMID: 29789522 Free PMC article.
Caspase-14 protects against epidermal UVB photodamage and water loss.
Denecker G, Hoste E, Gilbert B, Hochepied T, Ovaere P, Lippens S, Van den Broecke C, Van Damme P, D'Herde K, Hachem JP, Borgonie G, Presland RB, Schoonjans L, Libert C, Vandekerckhove J, Gevaert K, Vandenabeele P, Declercq W. Denecker G, et al. Among authors: hoste e. Nat Cell Biol. 2007 Jun;9(6):666-74. doi: 10.1038/ncb1597. Epub 2007 May 21. Nat Cell Biol. 2007. PMID: 17515931
Cell death in the skin.
Lippens S, Hoste E, Vandenabeele P, Agostinis P, Declercq W. Lippens S, et al. Among authors: hoste e. Apoptosis. 2009 Apr;14(4):549-69. doi: 10.1007/s10495-009-0324-z. Apoptosis. 2009. PMID: 19221876 Review.
Epicutaneous sensitization to house dust mite allergen requires interferon regulatory factor 4-dependent dermal dendritic cells.
Deckers J, Sichien D, Plantinga M, Van Moorleghem J, Vanheerswynghels M, Hoste E, Malissen B, Dombrowicz D, Guilliams M, De Bosscher K, Lambrecht BN, Hammad H. Deckers J, et al. Among authors: hoste e. J Allergy Clin Immunol. 2017 Nov;140(5):1364-1377.e2. doi: 10.1016/j.jaci.2016.12.970. Epub 2017 Feb 9. J Allergy Clin Immunol. 2017. PMID: 28189772
Epithelial HMGB1 Delays Skin Wound Healing and Drives Tumor Initiation by Priming Neutrophils for NET Formation.
Hoste E, Maueröder C, van Hove L, Catrysse L, Vikkula HK, Sze M, Maes B, Karjosukarso D, Martens L, Gonçalves A, Parthoens E, Roelandt R, Declercq W, Fuentes I, Palisson F, Gonzalez S, Salas-Alanis JC, Boon L, Huebener P, Mulder KW, Ravichandran K, Saeys Y, Schwabe RF, van Loo G. Hoste E, et al. Cell Rep. 2019 Nov 26;29(9):2689-2701.e4. doi: 10.1016/j.celrep.2019.10.104. Cell Rep. 2019. PMID: 31775038 Free article.
OTULIN Prevents Liver Inflammation and Hepatocellular Carcinoma by Inhibiting FADD- and RIPK1 Kinase-Mediated Hepatocyte Apoptosis.
Verboom L, Martens A, Priem D, Hoste E, Sze M, Vikkula H, Van Hove L, Voet S, Roels J, Maelfait J, Bongiovanni L, de Bruin A, Scott CL, Saeys Y, Pasparakis M, Bertrand MJM, van Loo G. Verboom L, et al. Among authors: hoste e. Cell Rep. 2020 Feb 18;30(7):2237-2247.e6. doi: 10.1016/j.celrep.2020.01.028. Cell Rep. 2020. PMID: 32075762 Free article.
Two distinct ubiquitin-binding motifs in A20 mediate its anti-inflammatory and cell-protective activities.
Martens A, Priem D, Hoste E, Vetters J, Rennen S, Catrysse L, Voet S, Deelen L, Sze M, Vikkula H, Slowicka K, Hochepied T, Iliaki K, Wullaert A, Janssens S, Lamkanfi M, Beyaert R, Armaka M, Bertrand MJM, van Loo G. Martens A, et al. Among authors: hoste e. Nat Immunol. 2020 Apr;21(4):381-387. doi: 10.1038/s41590-020-0621-9. Epub 2020 Mar 16. Nat Immunol. 2020. PMID: 32205881
Fibrotic enzymes modulate wound-induced skin tumorigenesis.
Van Hove L, Lecomte K, Roels J, Vandamme N, Vikkula HK, Hoorens I, Ongenae K, Hochepied T, Donati G, Saeys Y, Quist SR, Watt FM, van Loo G, Hoste E. Van Hove L, et al. Among authors: hoste e. EMBO Rep. 2021 May 5;22(5):e51573. doi: 10.15252/embr.202051573. Epub 2021 Mar 29. EMBO Rep. 2021. PMID: 33780134 Free PMC article.
OTULIN in NF-κB signaling, cell death, and disease.
Verboom L, Hoste E, van Loo G. Verboom L, et al. Among authors: hoste e. Trends Immunol. 2021 Jul;42(7):590-603. doi: 10.1016/j.it.2021.05.003. Epub 2021 May 29. Trends Immunol. 2021. PMID: 34074601 Review.
327 results