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How to measure the immunosuppressive activity of MDSC: assays, problems and potential solutions.
Bruger AM, Dorhoi A, Esendagli G, Barczyk-Kahlert K, van der Bruggen P, Lipoldova M, Perecko T, Santibanez J, Saraiva M, Van Ginderachter JA, Brandau S. Bruger AM, et al. Among authors: van ginderachter ja, van der bruggen p. Cancer Immunol Immunother. 2019 Apr;68(4):631-644. doi: 10.1007/s00262-018-2170-8. Epub 2018 May 21. Cancer Immunol Immunother. 2019. PMID: 29785656 Free PMC article. Review.
Identification of discrete tumor-induced myeloid-derived suppressor cell subpopulations with distinct T cell-suppressive activity.
Movahedi K, Guilliams M, Van den Bossche J, Van den Bergh R, Gysemans C, Beschin A, De Baetselier P, Van Ginderachter JA. Movahedi K, et al. Among authors: van den bossche j, van ginderachter ja, van den bergh r. Blood. 2008 Apr 15;111(8):4233-44. doi: 10.1182/blood-2007-07-099226. Epub 2008 Feb 13. Blood. 2008. PMID: 18272812 Free article.
Different tumor microenvironments contain functionally distinct subsets of macrophages derived from Ly6C(high) monocytes.
Movahedi K, Laoui D, Gysemans C, Baeten M, Stangé G, Van den Bossche J, Mack M, Pipeleers D, In't Veld P, De Baetselier P, Van Ginderachter JA. Movahedi K, et al. Among authors: van den bossche j, van ginderachter ja. Cancer Res. 2010 Jul 15;70(14):5728-39. doi: 10.1158/0008-5472.CAN-09-4672. Epub 2010 Jun 22. Cancer Res. 2010. PMID: 20570887
Interactions among myeloid regulatory cells in cancer.
Umansky V, Adema GJ, Baran J, Brandau S, Van Ginderachter JA, Hu X, Jablonska J, Mojsilovic S, Papadaki HA, Pico de Coaña Y, Santegoets KCM, Santibanez JF, Serre K, Si Y, Sieminska I, Velegraki M, Fridlender ZG. Umansky V, et al. Among authors: van ginderachter ja. Cancer Immunol Immunother. 2019 Apr;68(4):645-660. doi: 10.1007/s00262-018-2200-6. Epub 2018 Jul 12. Cancer Immunol Immunother. 2019. PMID: 30003321 Free PMC article. Review.
Myeloid-derived suppressor cells induce multiple myeloma cell survival by activating the AMPK pathway.
De Veirman K, Menu E, Maes K, De Beule N, De Smedt E, Maes A, Vlummens P, Fostier K, Kassambara A, Moreaux J, Van Ginderachter JA, De Bruyne E, Vanderkerken K, Van Valckenborgh E. De Veirman K, et al. Among authors: van ginderachter ja, van valckenborgh e. Cancer Lett. 2019 Feb 1;442:233-241. doi: 10.1016/j.canlet.2018.11.002. Epub 2018 Nov 9. Cancer Lett. 2019. PMID: 30419344
High Salt Inhibits Tumor Growth by Enhancing Anti-tumor Immunity.
Willebrand R, Hamad I, Van Zeebroeck L, Kiss M, Bruderek K, Geuzens A, Swinnen D, Côrte-Real BF, Markó L, Lebegge E, Laoui D, Kemna J, Kammertoens T, Brandau S, Van Ginderachter JA, Kleinewietfeld M. Willebrand R, et al. Among authors: van zeebroeck l, van ginderachter ja. Front Immunol. 2019 Jun 4;10:1141. doi: 10.3389/fimmu.2019.01141. eCollection 2019. Front Immunol. 2019. PMID: 31214164 Free PMC article.
Therapeutic depletion of CCR8+ tumor-infiltrating regulatory T cells elicits antitumor immunity and synergizes with anti-PD-1 therapy.
Van Damme H, Dombrecht B, Kiss M, Roose H, Allen E, Van Overmeire E, Kancheva D, Martens L, Murgaski A, Bardet PMR, Blancke G, Jans M, Bolli E, Martins MS, Elkrim Y, Dooley J, Boon L, Schwarze JK, Tacke F, Movahedi K, Vandamme N, Neyns B, Ocak S, Scheyltjens I, Vereecke L, Nana FA, Merchiers P, Laoui D, Van Ginderachter JA. Van Damme H, et al. Among authors: van ginderachter ja, van overmeire e. J Immunother Cancer. 2021 Feb;9(2):e001749. doi: 10.1136/jitc-2020-001749. J Immunother Cancer. 2021. PMID: 33589525 Free PMC article.
152 results